The Genetic Basis of Preeclampsia in an Andean Population Adapted to High Altitude

Type: Population Genomics
Archiver: European Genome-Phenome Archive (EGA)

5 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001007801	Fastq files generated during target sequencing of 10MB genomic region surrounding top hits in GWAS in a subset of 86 individuals in case families. Paired end sequencing performed on Illumina NextSeq.	NextSeq 500	86
EGAD00010002124	Genotypes generated for Puno cohort Batch 2. Case (PRE) and control (PUN) families were recruited in hospital. Raw genotypes no QC. Includes unrelated genotyping controls (HG).	Affymetrix Axiom LAT	467
EGAD00010002125	Phenotypes from case families listed in medical records and used in analyses.		558
EGAD00010002126	Genotypes generated for Puno cohort Batch 1. Case (PRE) and control (PUN) families were recruited in hospital, and additional unrelated controls were recruited in university (UNA). Raw genotypes no QC.	Affymetrix Axiom LAT	480
EGAD00010002127	Combined genotypes for Batch 1 and 2 after quality control. All individuals included in analyses.	Affymetrix Axiom LAT	877

Publications	Citations
Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes. Nieves-Colón MA, Badillo Rivera KM, Sandoval K, Villanueva Dávalos V, Enriquez Lencinas LE, Mendoza-Revilla J, Adhikari K, González-Buenfil R, Chen JW, Zhang ET, Sockell A, Ortiz-Tello P, Hurtado GM, Condori Salas R, Cebrecos R, Manzaneda Choque JC, Manzaneda Choque FP, Yábar Pilco GP, Rawls E, Eng C, Huntsman S, Burchard E, Ruiz-Linares A, González-José R, Bedoya G, Rothhammer F, Bortolini MC, Poletti G, Gallo C, Bustamante CD, Baker JC, Gignoux CR, Wojcik GL, Moreno-Estrada A. Am J Hum Genet 109: 2022 1117-1139	6

Publications

Citations

Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes.
Nieves-Colón MA, Badillo Rivera KM, Sandoval K, Villanueva Dávalos V, Enriquez Lencinas LE, Mendoza-Revilla J, Adhikari K, González-Buenfil R, Chen JW, Zhang ET, Sockell A, Ortiz-Tello P, Hurtado GM, Condori Salas R, Cebrecos R, Manzaneda Choque JC, Manzaneda Choque FP, Yábar Pilco GP, Rawls E, Eng C, Huntsman S, Burchard E, Ruiz-Linares A, González-José R, Bedoya G, Rothhammer F, Bortolini MC, Poletti G, Gallo C, Bustamante CD, Baker JC, Gignoux CR, Wojcik GL, Moreno-Estrada A. Am J Hum Genet 109: 2022 1117-1139