RNA-sequencing of Non-muscle Invasive Bladder cancer (NMIBC)

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Dataset ID	Description	Technology	Samples
EGAD00001007005	Paired-end RNA-sequencing of tumour tissue samples (n=85) from primary urothelial bladder cancer patients. Sequencing was performed using either HiSeq (n=27) or NextSeq (n=58) Illumina platforms. Of the 85 samples, 78 are Non-muscle invasive (NMIBC) and 7 are Muscle invasive (MIBC).	Illumina HiSeq 2500 NextSeq 550	85

Publications	Citations
Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients. Goel A, Ward DG, Gordon NS, Abbotts B, Zeegers MP, Cheng KK, James ND, Bryan RT, Arnold R. Front Oncol 10: 2020 812	9
PD-L2 Is Constitutively Expressed in Normal and Malignant Urothelium. Dowell AC, Munford H, Goel A, Gordon NS, James ND, Cheng KK, Zeegers MP, Ward DG, Bryan RT. Front Oncol 11: 2021 626748	7
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer. Lindskrog SV, Prip F, Lamy P, Taber A, Groeneveld CS, Birkenkamp-Demtröder K, Jensen JB, Strandgaard T, Nordentoft I, Christensen E, Sokac M, Birkbak NJ, Maretty L, Hermann GG, Petersen AC, Weyerer V, Grimm MO, Horstmann M, Sjödahl G, Höglund M, Steiniche T, Mogensen K, de Reyniès A, Nawroth R, Jordan B, Lin X, Dragicevic D, Ward DG, Goel A, Hurst CD, Raman JD, Warrick JI, Segersten U, Sikic D, van Kessel KEM, Maurer T, Meeks JJ, DeGraff DJ, Bryan RT, Knowles MA, Simic T, Hartmann A, Zwarthoff EC, Malmström PU, Malats N, Real FX, Dyrskjøt L. Nat Commun 12: 2021 2301	120
The Sirenic Links between Diabetes, Obesity, and Bladder Cancer. Gill E, Sandhu G, Ward DG, Perks CM, Bryan RT. Int J Mol Sci 22: 2021 11150	10
STAG2 Protein Expression in Non-muscle-invasive Bladder Cancer: Associations with Sex, Genomic and Transcriptomic Changes, and Clinical Outcomes. Gordon NS, Humayun-Zakaria N, Goel A, Abbotts B, Zeegers MP, Cheng KK, James ND, Arnold R, Bryan RT, Ward DG. Eur Urol Open Sci 38: 2022 88-95	5
Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes. Goel A, Ward DG, Noyvert B, Yu M, Gordon NS, Abbotts B, Colbourne JK, Kissane S, James ND, Zeegers MP, Cheng KK, Cazier JB, Whalley CM, Beggs AD, Palles C, Arnold R, Bryan RT. Genome Med 14: 2022 59	5