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SYNTHETIC DATA: EOSC4Cancer Colorectal Cancer (CRC) synthetic Whole Genome Sequencing dataset

This dataset contains 10 tumor and normal pairs synthetic WGS data of colorectal cancer that were simulated in a standard format of Illumina paired-end reads. NEAT read simulator (version 3.0, https://github.com/zstephens/neat-genreads) is utilized to synthetize these 10 pairs tumor and normal WGS data. In the procedure of data generation, simulated parameters (i.e., sequencing error statistics, read fragment length distribution and GC% coverage bias) are learned from data models provided by NEAT. The average sequencing depth for tumor and normal samples aims to reach around 110X and 60X, respectively. For generation of synthetic normal WGS data per each sample, a germline variant profile from a real patient is down-sampled randomly, which includes 50% germline variants of such a patient. It is then mixed together with an in silico germline variant profile that is modelled randomly using an average mutation rate (0.001), finally constituting a full germline profile for normal synthetic WGS data. For generation of synthetic tumor WGS data per each sample, a pre-defined somatic short variant profile (SNVs+Indels) learn from a real CRC patient is added to the germline variant profile used for creating normal synthetic WGS data of the same patient, which is utilized to produce simulated sequences. Neither copy number profile nor structural variation profile is introduced into the tumor synthetic WGS data. Tumor content and ploidy are assumed to be 100% and 2.

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Access policy for SYNTHETIC DATA in FEGA Norway test instance

The synthetic data is approved for research and explorations of data sharing infrastructures and bioinformatics workflows.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000386 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000105649 fastq.gz 6.5 GB
EGAF50000105650 fastq.gz 6.5 GB
EGAF50000105651 fastq.gz 6.5 GB
EGAF50000105652 fastq.gz 6.5 GB
EGAF50000105653 fastq.gz 6.5 GB
EGAF50000105654 fastq.gz 6.5 GB
EGAF50000105655 fastq.gz 6.5 GB
EGAF50000105656 fastq.gz 6.5 GB
EGAF50000105657 fastq.gz 11.9 GB
EGAF50000105658 fastq.gz 11.9 GB
EGAF50000105659 fastq.gz 11.9 GB
EGAF50000105660 fastq.gz 11.9 GB
EGAF50000105661 fastq.gz 11.9 GB
EGAF50000105662 fastq.gz 11.9 GB
EGAF50000105663 fastq.gz 11.9 GB
EGAF50000105664 fastq.gz 11.9 GB
EGAF50000105666 fastq.gz 6.5 GB
EGAF50000105667 fastq.gz 6.5 GB
EGAF50000105668 fastq.gz 6.5 GB
EGAF50000105669 fastq.gz 6.5 GB
EGAF50000105670 fastq.gz 6.5 GB
EGAF50000105671 fastq.gz 6.5 GB
EGAF50000105672 fastq.gz 6.5 GB
EGAF50000105673 fastq.gz 6.5 GB
EGAF50000105674 fastq.gz 11.9 GB
EGAF50000105675 fastq.gz 11.9 GB
EGAF50000105676 fastq.gz 11.9 GB
EGAF50000105677 fastq.gz 11.9 GB
EGAF50000105678 fastq.gz 11.9 GB
EGAF50000105679 fastq.gz 11.9 GB
EGAF50000105680 fastq.gz 11.9 GB
EGAF50000105681 fastq.gz 11.9 GB
EGAF50000105682 fastq.gz 6.6 GB
EGAF50000105683 fastq.gz 6.6 GB
EGAF50000105684 fastq.gz 6.6 GB
EGAF50000105685 fastq.gz 6.6 GB
EGAF50000105686 fastq.gz 6.6 GB
EGAF50000105687 fastq.gz 6.6 GB
EGAF50000105688 fastq.gz 6.6 GB
EGAF50000105689 fastq.gz 6.6 GB
EGAF50000105690 fastq.gz 12.0 GB
EGAF50000105691 fastq.gz 12.0 GB
EGAF50000105692 fastq.gz 12.0 GB
EGAF50000105693 fastq.gz 12.0 GB
EGAF50000105694 fastq.gz 12.0 GB
EGAF50000105695 fastq.gz 12.0 GB
EGAF50000105696 fastq.gz 12.0 GB
EGAF50000105697 fastq.gz 12.0 GB
EGAF50000105698 fastq.gz 6.6 GB
EGAF50000105699 fastq.gz 6.6 GB
EGAF50000105700 fastq.gz 6.6 GB
EGAF50000105701 fastq.gz 6.6 GB
EGAF50000105702 fastq.gz 6.6 GB
EGAF50000105703 fastq.gz 6.6 GB
EGAF50000105704 fastq.gz 6.6 GB
EGAF50000105705 fastq.gz 6.6 GB
EGAF50000105706 fastq.gz 12.0 GB
EGAF50000105707 fastq.gz 12.0 GB
EGAF50000105708 fastq.gz 12.0 GB
EGAF50000105709 fastq.gz 12.0 GB
EGAF50000105710 fastq.gz 12.0 GB
EGAF50000105711 fastq.gz 12.0 GB
EGAF50000105712 fastq.gz 12.0 GB
EGAF50000105713 fastq.gz 12.0 GB
EGAF50000105714 fastq.gz 6.6 GB
EGAF50000105715 fastq.gz 6.6 GB
EGAF50000105716 fastq.gz 6.6 GB
EGAF50000105717 fastq.gz 6.6 GB
EGAF50000105718 fastq.gz 6.6 GB
EGAF50000105719 fastq.gz 6.6 GB
EGAF50000105720 fastq.gz 6.6 GB
EGAF50000105721 fastq.gz 6.6 GB
EGAF50000105722 fastq.gz 12.0 GB
EGAF50000105723 fastq.gz 12.0 GB
EGAF50000105724 fastq.gz 12.0 GB
EGAF50000105725 fastq.gz 12.0 GB
EGAF50000105726 fastq.gz 12.0 GB
EGAF50000105727 fastq.gz 12.0 GB
EGAF50000105728 fastq.gz 12.0 GB
EGAF50000105729 fastq.gz 12.0 GB
EGAF50000105730 fastq.gz 6.6 GB
EGAF50000105731 fastq.gz 6.6 GB
EGAF50000105732 fastq.gz 6.6 GB
EGAF50000105733 fastq.gz 6.6 GB
EGAF50000105734 fastq.gz 6.6 GB
EGAF50000105735 fastq.gz 6.6 GB
EGAF50000105736 fastq.gz 6.6 GB
EGAF50000105737 fastq.gz 6.6 GB
EGAF50000105738 fastq.gz 12.0 GB
EGAF50000105739 fastq.gz 12.0 GB
EGAF50000105740 fastq.gz 12.0 GB
EGAF50000105741 fastq.gz 12.0 GB
EGAF50000105742 fastq.gz 12.0 GB
EGAF50000105743 fastq.gz 12.0 GB
EGAF50000105744 fastq.gz 12.0 GB
EGAF50000105745 fastq.gz 12.0 GB
EGAF50000105746 fastq.gz 6.6 GB
EGAF50000105747 fastq.gz 6.6 GB
EGAF50000105748 fastq.gz 6.6 GB
EGAF50000105749 fastq.gz 6.6 GB
EGAF50000105750 fastq.gz 6.6 GB
EGAF50000105751 fastq.gz 6.6 GB
EGAF50000105752 fastq.gz 6.6 GB
EGAF50000105753 fastq.gz 6.6 GB
EGAF50000105754 fastq.gz 12.0 GB
EGAF50000105755 fastq.gz 12.0 GB
EGAF50000105756 fastq.gz 12.0 GB
EGAF50000105757 fastq.gz 12.0 GB
EGAF50000105758 fastq.gz 12.0 GB
EGAF50000105759 fastq.gz 12.0 GB
EGAF50000105760 fastq.gz 12.0 GB
EGAF50000105761 fastq.gz 12.0 GB
EGAF50000105762 fastq.gz 6.5 GB
EGAF50000105763 fastq.gz 6.5 GB
EGAF50000105764 fastq.gz 6.5 GB
EGAF50000105765 fastq.gz 6.5 GB
EGAF50000105766 fastq.gz 6.5 GB
EGAF50000105767 fastq.gz 6.5 GB
EGAF50000105768 fastq.gz 6.5 GB
EGAF50000105769 fastq.gz 6.5 GB
EGAF50000105770 fastq.gz 11.9 GB
EGAF50000105771 fastq.gz 11.9 GB
EGAF50000105772 fastq.gz 11.9 GB
EGAF50000105773 fastq.gz 11.9 GB
EGAF50000105774 fastq.gz 11.9 GB
EGAF50000105775 fastq.gz 11.9 GB
EGAF50000105776 fastq.gz 11.9 GB
EGAF50000105777 fastq.gz 11.9 GB
EGAF50000105779 fastq.gz 6.6 GB
EGAF50000105780 fastq.gz 6.6 GB
EGAF50000105781 fastq.gz 6.6 GB
EGAF50000105782 fastq.gz 6.6 GB
EGAF50000105783 fastq.gz 6.6 GB
EGAF50000105784 fastq.gz 6.6 GB
EGAF50000105785 fastq.gz 6.6 GB
EGAF50000105786 fastq.gz 6.6 GB
EGAF50000105787 fastq.gz 12.0 GB
EGAF50000105788 fastq.gz 12.0 GB
EGAF50000105789 fastq.gz 12.0 GB
EGAF50000105790 fastq.gz 12.0 GB
EGAF50000105791 fastq.gz 12.0 GB
EGAF50000105792 fastq.gz 12.0 GB
EGAF50000105793 fastq.gz 12.0 GB
EGAF50000105794 fastq.gz 12.0 GB
EGAF50000105795 fastq.gz 6.6 GB
EGAF50000105796 fastq.gz 6.6 GB
EGAF50000105797 fastq.gz 6.6 GB
EGAF50000105798 fastq.gz 6.6 GB
EGAF50000105799 fastq.gz 6.6 GB
EGAF50000105800 fastq.gz 6.6 GB
EGAF50000105801 fastq.gz 6.6 GB
EGAF50000105802 fastq.gz 6.6 GB
EGAF50000105803 fastq.gz 12.0 GB
EGAF50000105804 fastq.gz 12.0 GB
EGAF50000105805 fastq.gz 12.0 GB
EGAF50000105806 fastq.gz 12.0 GB
EGAF50000105807 fastq.gz 12.0 GB
EGAF50000105808 fastq.gz 12.0 GB
EGAF50000105809 fastq.gz 12.0 GB
EGAF50000105810 fastq.gz 12.0 GB
EGAF50000105811 tbi 1.9 MB
EGAF50000105812 vcf.gz 282.5 MB
EGAF50000105813 csv 605 Bytes
EGAF50000106043 vcf.gz 30.1 MB
EGAF50000106044 vcf.gz 30.0 MB
EGAF50000106045 vcf.gz 30.0 MB
EGAF50000106046 vcf.gz 30.1 MB
EGAF50000106047 vcf.gz 30.2 MB
EGAF50000106048 vcf.gz 30.1 MB
EGAF50000106049 vcf.gz 30.1 MB
EGAF50000106050 vcf.gz 30.1 MB
EGAF50000106051 vcf.gz 30.0 MB
EGAF50000106052 vcf.gz 30.0 MB
EGAF50000106053 vcf.gz 193.6 kB
EGAF50000106054 vcf.gz 229.9 kB
EGAF50000106055 vcf.gz 223.4 kB
EGAF50000106056 vcf.gz 953.4 kB
EGAF50000106057 vcf.gz 209.1 kB
EGAF50000106058 vcf.gz 232.4 kB
EGAF50000106059 vcf.gz 200.4 kB
EGAF50000106060 vcf.gz 142.1 kB
EGAF50000106061 vcf.gz 306.1 kB
EGAF50000106062 vcf.gz 187.1 kB
183 Files (1.5 TB)