VRK3 depletion in Pontine Diffuse Midline Glioma DMG-K27 altered cells
In order to investigate possible mechanisms underlying the phenotype of cell fitness decline observed following decrease of VRK3 in pontine DMG-K27 altered cells 7, we examined differences in global gene expression. RNA-seq was performed 44h and 60h post-transduction with two distinct shRNAs targeting VRK3 to be able to evaluate the early impact of VRK3 knock-down (KD) in four independent in vitro models of DMG
- 36 samples
- DAC: EGAC00001003123
- Technology: Illumina NovaSeq 6000
This data use modifier indicates that use of the data is limited to not-for-profit organizations. This data use modifier indicates that use of the data is limited to not-for-profit use. This requirement indicates that requestor agrees not to publish results of studies until a specific date. This requirement indicates that the requestor must agree to collaboration with the primary study investigator(s).
DUO:0000045 DUO:0000046 DUO:0000024 DUO:0000020
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| RNASeq |