Genomics and Oncogenesis of Pediatric Brain Tumors

Request Access

Dataset ID	Description	Technology	Samples
EGAD00001010097	In order to investigate possible mechanisms underlying the phenotype of cell fitness decline observed following decrease of VRK3 in pontine DMG-K27 altered cells 7, we examined differences in global gene expression. RNA-seq was performed 44h and 60h post-transduction with two distinct shRNAs targeting VRK3 to be able to evaluate the early impact of VRK3 knock-down (KD) in four independent in vitro models of DMG	Illumina NovaSeq 6000	36