Multi-region sequencing of 10 neuroblastoma cases
To investigate intratumour heterogeneity and to better understand tumour evolution in neuroblastoma, we have performed a multi-region whole-exome sequencing on a total of 51 spatially separated tumor samples from 9 primary neuroblastomas (2 low-risk, 1 intermediate-risk and 6 high-risk) and 1 relapsed neuroblastoma. We also assessed the impact of chemotherapy on the clonal expansion by sequencing tumour regions from one medium risk and one high-risk tumour for which we had matched samples obtained at diagnosis and after chemotherapy.
- 61 samples
- DAC: EGAC00001001766
- Technology: Illumina HiSeq 4000
Data Access Committee for all sequencing data obtained at the Charite Berlin hospital for Paediatric Oncology
Access to the raw data is managed by the data access committee. To request access, a principal investigator (PI) needs to provide a brief description (1-2 paragraphs) of the planned research project to the data access committee. PIs that have been granted access by the data access committee may enable members of their research group to access the data but are not allowed to further distribute any of the data files.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00004723158 | fastq.bz2 | 6.5 GB | ||
| EGAF00004723159 | fastq.bz2 | 6.5 GB | ||
| EGAF00004723160 | fastq.bz2 | 8.1 GB | ||
| EGAF00004723161 | fastq.bz2 | 8.0 GB | ||
| EGAF00004723162 | fastq.bz2 | 7.5 GB | ||
| EGAF00004723163 | fastq.bz2 | 7.5 GB | ||
| EGAF00004723164 | fastq.bz2 | 8.1 GB | ||
| EGAF00004723165 | fastq.bz2 | 8.1 GB | ||
| EGAF00004723166 | fastq.bz2 | 5.5 GB | ||
| EGAF00004723167 | fastq.bz2 | 5.5 GB | ||
| EGAF00004723168 | fastq.bz2 | 5.5 GB | ||
| EGAF00004723169 | fastq.bz2 | 5.4 GB | ||
| EGAF00004723170 | fastq.bz2 | 4.4 GB | ||
| EGAF00004723171 | fastq.bz2 | 4.4 GB | ||
| EGAF00004723172 | fastq.bz2 | 7.3 GB | ||
| EGAF00004723173 | fastq.bz2 | 7.3 GB | ||
| EGAF00004723174 | fastq.bz2 | 5.4 GB | ||
| EGAF00004723175 | fastq.bz2 | 5.3 GB | ||
| EGAF00004723176 | fastq.bz2 | 5.4 GB | ||
| EGAF00004723177 | fastq.bz2 | 5.4 GB | ||
| EGAF00004723178 | fastq.bz2 | 6.2 GB | ||
| EGAF00004723179 | fastq.bz2 | 6.1 GB | ||
| EGAF00004723180 | fastq.bz2 | 7.7 GB | ||
| EGAF00004723181 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723182 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723183 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723184 | fastq.bz2 | 5.0 GB | ||
| EGAF00004723185 | fastq.bz2 | 4.9 GB | ||
| EGAF00004723186 | fastq.bz2 | 5.2 GB | ||
| EGAF00004723187 | fastq.bz2 | 5.2 GB | ||
| EGAF00004723188 | fastq.bz2 | 4.3 GB | ||
| EGAF00004723189 | fastq.bz2 | 4.3 GB | ||
| EGAF00004723190 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723191 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723192 | fastq.bz2 | 8.3 GB | ||
| EGAF00004723193 | fastq.bz2 | 8.2 GB | ||
| EGAF00004723194 | fastq.bz2 | 6.2 GB | ||
| EGAF00004723195 | fastq.bz2 | 6.3 GB | ||
| EGAF00004723196 | fastq.bz2 | 7.4 GB | ||
| EGAF00004723197 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723198 | fastq.bz2 | 7.7 GB | ||
| EGAF00004723199 | fastq.bz2 | 7.8 GB | ||
| EGAF00004723200 | fastq.bz2 | 7.4 GB | ||
| EGAF00004723201 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723202 | fastq.bz2 | 10.8 GB | ||
| EGAF00004723203 | fastq.bz2 | 10.9 GB | ||
| EGAF00004723204 | fastq.bz2 | 8.4 GB | ||
| EGAF00004723205 | fastq.bz2 | 8.4 GB | ||
| EGAF00004723206 | fastq.bz2 | 8.1 GB | ||
| EGAF00004723207 | fastq.bz2 | 8.0 GB | ||
| EGAF00004723208 | fastq.bz2 | 6.4 GB | ||
| EGAF00004723209 | fastq.bz2 | 6.3 GB | ||
| EGAF00004723210 | fastq.bz2 | 8.5 GB | ||
| EGAF00004723211 | fastq.bz2 | 8.5 GB | ||
| EGAF00004723212 | fastq.bz2 | 7.9 GB | ||
| EGAF00004723213 | fastq.bz2 | 7.9 GB | ||
| EGAF00004723214 | fastq.bz2 | 7.4 GB | ||
| EGAF00004723215 | fastq.bz2 | 7.3 GB | ||
| EGAF00004723216 | fastq.bz2 | 7.1 GB | ||
| EGAF00004723217 | fastq.bz2 | 7.1 GB | ||
| EGAF00004723218 | fastq.bz2 | 9.3 GB | ||
| EGAF00004723219 | fastq.bz2 | 9.3 GB | ||
| EGAF00004723220 | fastq.bz2 | 7.6 GB | ||
| EGAF00004723221 | fastq.bz2 | 7.5 GB | ||
| EGAF00004723222 | fastq.bz2 | 5.0 GB | ||
| EGAF00004723223 | fastq.bz2 | 5.0 GB | ||
| EGAF00004723224 | fastq.bz2 | 11.9 GB | ||
| EGAF00004723225 | fastq.bz2 | 12.1 GB | ||
| EGAF00004723226 | fastq.bz2 | 5.3 GB | ||
| EGAF00004723227 | fastq.bz2 | 5.2 GB | ||
| EGAF00004723228 | fastq.bz2 | 8.6 GB | ||
| EGAF00004723229 | fastq.bz2 | 8.5 GB | ||
| EGAF00004723230 | fastq.bz2 | 9.0 GB | ||
| EGAF00004723231 | fastq.bz2 | 8.9 GB | ||
| EGAF00004723232 | fastq.bz2 | 12.1 GB | ||
| EGAF00004723233 | fastq.bz2 | 12.3 GB | ||
| EGAF00004723234 | fastq.bz2 | 15.6 GB | ||
| EGAF00004723235 | fastq.bz2 | 15.9 GB | ||
| EGAF00004723236 | fastq.bz2 | 13.2 GB | ||
| EGAF00004723237 | fastq.bz2 | 13.4 GB | ||
| EGAF00004723238 | fastq.bz2 | 9.2 GB | ||
| EGAF00004723239 | fastq.bz2 | 9.7 GB | ||
| EGAF00004723240 | fastq.bz2 | 10.9 GB | ||
| EGAF00004723241 | fastq.bz2 | 11.1 GB | ||
| EGAF00004723242 | fastq.bz2 | 10.7 GB | ||
| EGAF00004723243 | fastq.bz2 | 10.9 GB | ||
| EGAF00004723244 | fastq.bz2 | 11.9 GB | ||
| EGAF00004723245 | fastq.bz2 | 12.1 GB | ||
| EGAF00004723246 | fastq.bz2 | 9.8 GB | ||
| EGAF00004723247 | fastq.bz2 | 10.0 GB | ||
| EGAF00004723248 | fastq.bz2 | 11.1 GB | ||
| EGAF00004723249 | fastq.bz2 | 11.3 GB | ||
| EGAF00004723250 | fastq.bz2 | 8.4 GB | ||
| EGAF00004723251 | fastq.bz2 | 8.5 GB | ||
| EGAF00004723252 | fastq.bz2 | 9.5 GB | ||
| EGAF00004723253 | fastq.bz2 | 9.6 GB | ||
| EGAF00004723254 | fastq.bz2 | 8.6 GB | ||
| EGAF00004723255 | fastq.bz2 | 8.9 GB | ||
| EGAF00004723256 | fastq.bz2 | 9.2 GB | ||
| EGAF00004723257 | fastq.bz2 | 9.7 GB | ||
| EGAF00004723258 | fastq.bz2 | 7.5 GB | ||
| EGAF00004723259 | fastq.bz2 | 7.7 GB | ||
| EGAF00004723260 | fastq.bz2 | 7.4 GB | ||
| EGAF00004723261 | fastq.bz2 | 7.7 GB | ||
| EGAF00004723262 | fastq.bz2 | 10.4 GB | ||
| EGAF00004723263 | fastq.bz2 | 10.8 GB | ||
| EGAF00004723264 | fastq.bz2 | 11.4 GB | ||
| EGAF00004723265 | fastq.bz2 | 11.7 GB | ||
| EGAF00004723266 | fastq.bz2 | 9.2 GB | ||
| EGAF00004723267 | fastq.bz2 | 9.2 GB | ||
| EGAF00004723268 | fastq.bz2 | 10.2 GB | ||
| EGAF00004723269 | fastq.bz2 | 10.4 GB | ||
| EGAF00004723270 | fastq.bz2 | 10.2 GB | ||
| EGAF00004723271 | fastq.bz2 | 10.4 GB | ||
| EGAF00004723272 | fastq.bz2 | 8.5 GB | ||
| EGAF00004723273 | fastq.bz2 | 8.7 GB | ||
| EGAF00004723274 | fastq.bz2 | 12.5 GB | ||
| EGAF00004723275 | fastq.bz2 | 12.7 GB | ||
| EGAF00004723276 | fastq.bz2 | 11.5 GB | ||
| EGAF00004723277 | fastq.bz2 | 11.6 GB | ||
| EGAF00004723278 | fastq.bz2 | 10.6 GB | ||
| EGAF00004723279 | fastq.bz2 | 10.9 GB | ||
| 122 Files (1.0 TB) | ||||