Molecular Characterization of the Immunological Landscape in Human Brain Tumors

We are performing a comprehensive cellular and molecular characterization of the immunological landscape of human brain tumors. This work includes single-cell RNA and T cell receptor (TCR) sequencing of T cells isolated from the tumor and blood of patients with advanced primary (high-grade glioma) and metastatic (non-small cell lung cancer) cancers. Whole exome sequencing on tumor and normal tissue was also performed.

• Type: Cohort
• Archive: The database of Genotypes and Phenotypes (dbGaP)