Uncovering Colorectal Cancer Etiology and Biology by Integrating Proteomics with Other Omics Data

This study included the expression profiling of approximately 10,000 proteins generated in normal colon tissue samples collected from 323 participants of European descent, paired with genome-wide genotype data obtained from blood samples. Using these proteomics and genotype datasets, we developed genetically prediction models for protein expression and conducted a proteome-wide association study (PWAS) of colorectal cancer (CRC) in European populations to identify proteins associated with CRC risk.

• Type: Cohort
• Archive: The database of Genotypes and Phenotypes (dbGaP)