Spatial transcriptome analysis of aging of healthy skin samples

Previous studies have revealed that skin T cells accumulate and maintain immune responses in the elderly. However, we questioned why these functional T cells fail to recognize and eliminate malignant cells, making elderly skin more prone to developing malignant tumors. To address this question, we examined the overall skin microenvironment in aging using Xenium digital spatial RNA sequencing.

• Type: Cohort
• Archiver: Japanese Genotype-phenotype Archive (JGA)