Whole exome sequencing of patients with esophageal squamous cell carcinoma receiving chemoradiotherapy

We performed multi-region whole exome sequencing (WES) of pre-treatment and recurrent esophageal cancer receiving chemoradiotherapy in order to characterize clonal evolution of treatment resistant clones. Furthermore, additional solitary pre-treatment tumor samples were subjected to WES to detect biomarkers predicting clinical outcome.

• Type: Tumor vs. Matched-Normal
• Archiver: Japanese Genotype-phenotype Archive (JGA)