RSV infection of primary bronchial epithelial cells in asthma

Primary bronchial epithelial cells derived from healthy donors and asthma patients were differentiated in Air-Liquid-Interface condition and infected with the respiratory syncytial virus. Single-cell RNA sequencing analysis of these cultures was used to study the transcriptomic response of the cells to RSV.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001011264	This dataset contains the count matrices and corresponding metadata for our study on bronchial epithelial cells response to RSV in healthy and in asthma. This scRNAseq data is from primary cells, that have been differentiated in ALI cultures and infected with RSV.	Illumina NovaSeq 6000	8

Publications	Citations
Airway epithelial cell response to RSV is mostly impaired in goblet and multiciliated cells in asthma. Gay ACA, Banchero M, Carpaij O, Kole TM, Apperloo L, van Gosliga D, Fajar PA, Koppelman GH, Bont L, Hendriks RW, van den Berge M, Nawijn MC. Thorax 79: 2024 811-821	0