The_effects_of_chemotherapy_and_radiation_in_human_oesophageal_epithelium

Human oesophagus is a patchwork of competing mutant clones. We wish to see how this patchwork is altered under the extreme selection pressures of chemotherapy and radiotherapy both individually and combined. We will sequence 2mm2 contiguous pieces of oesophageal epithelium from patients who have undergone chemotherapy and radiotherapy to assess how the mutational landscape has changed.

• Type: Cancer Genomics
• Archive: European Genome-phenome Archive (EGA)