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Mutational_burden_in_oesophagus_following_chemotherapy_and_radiotherapy_treatment_WGS

We wish to assess the changes in signature and mutational burden in patients who have undergone either chemotherapy or chemotherapy + radiotherapy. Using duplex sequencing will assess the mutational landscape in oesophageal epithelia in patients who have undergone these treatment regimes.

Publications Citations
Cancer treatment alters mutant selection in normal esophagus.
Nat Genet 58: 2026 2566-2578
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