The genomic landscape of recurrent ovarian high grade serous carcinoma: the BriTROC-1 study
The BriTROC-1 study, spanning 15 centres across the United Kingdom, is a prospective observational project investigating putative causes of relapse in high-grade serous carcinoma (HGSC). Potential genomic changes associated with disease recurrence are examined by studying paired tumour samples collected from patients at diagnosis and after relapse after receiving platinum based chemotherapy. Shallow whole genome sequencing and targeted amplicon sequencing are used to identify copy number aberrations and short variants respectively.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001011049 | Illumina HiSeq 2500 Illumina HiSeq 4000 | 679 | |
EGAD00001011058 | Illumina HiSeq 2500 Illumina HiSeq 4000 Illumina MiSeq | 933 |
Publications | Citations |
---|---|
Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.
Nat Commun 14: 2023 6505 |
4 |