Papua New Guinean Genome Altitude Project

2 Datasets 3 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001010142	The PGAP dataset 2 includes 82 whole genome sequences for Papua New Guinean individuals sampled in Daru (N=1), Port Moresby (N=64) and Mount Wilhelm (N=17). DNA was extracted from saliva samples (Oragen kit). Sequencing libraries were prepared using the TruSeq DNA PCR-Free HT kit. 150 bp paired-end sequencing was performed on the Illumina HiSeq X5 sequencer. The PGAP dataset provides Fastq, mapped cram files (GRCh38) and phenotype measurements.	HiSeq X Five	82
EGAD00001010143	The PGAP dataset 1 includes 81 whole genome sequences for Papua New Guinean individuals sampled in Daru (N=38) and Mount Wilhelm (N=43). DNA was extrated from saliva samples (Oragen kit). Sequencing libraries were prepared using the TruSeq DNA PCR-Free HT kit. 150 bp paired-end sequencing was performed on the Illumina HiSeq X5 sequencer. The PGAP dataset provides Fastq, mapped cram files (GRCh38) and phenotype measurements.	HiSeq X Five	81

Publications	Citations
Positive selection in the genomes of two Papua New Guinean populations at distinct altitude levels. André M, Brucato N, Hudjasov G, Pankratov V, Yermakovich D, Montinaro F, Kreevan R, Kariwiga J, Muke J, Boland A, Deleuze JF, Meyer V, Evans N, Cox MP, Leavesley M, Dannemann M, Org T, Metspalu M, Mondal M, Ricaut FX. Nat Commun 15: 2024 3352	13
Influence of betel nut chewing on oral microbiome in Papua New Guinea. Brucato N, Lisant V, Kinipi C, Kik A, Besnard G, Leavesley M, Ricaut FX. Evol Med Public Health 13: 2025 36-44	1
Resolving out of Africa event for Papua New Guinean population using neural network. Mondal M, André M, Pathak AK, Brucato N, Ricaut FX, Metspalu M, Eriksson A. Nat Commun 16: 2025 6345	2