Single-cell RNA and ATAC sequencing data analysis of human postmenopausal fallopian tube and ovary

In this study, we used a combination of technologies, including Drop-seq, 10X single-cell RNA-seq (scRNA-seq), and single-cell assay on transposase accessible chromatin (scATAC-seq) to generate a high-quality cell atlas that consists of four tissue sites from the reproductive tract of postmenopausal women. This atlas, by far the most comprehensive map of the postmenopausal female reproductive system to date, will pave the way to a better understanding of the pathophysiology of many diseases affecting older women.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001010076	This datasets contains raw sequencing fastq data of 17 samples from 7 donors of single cell RNA using10x genome technology of human postmenopausal fallopian tube and ovary tissues.	NextSeq 500	17
EGAD00001010077	This datasets contains raw sequencing fastq data of14 samples from 5 donors of single cell ATAC using10x genome technology of human postmenopausal fallopian tube and ovary tissues.	NextSeq 500	14

Publications	Citations
A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing. Lengyel E, Li Y, Weigert M, Zhu L, Eckart H, Javellana M, Ackroyd S, Xiao J, Olalekan S, Glass D, Iyer S, Krishnan R, Bilecz AJ, Lastra R, Chen M, Basu A. Cell Rep 41: 2022 111838	13