in silico drug target prediction for melanoma
The in silico single gene deletion step was adapted to simulate the knock-out of all targets of a drug on an objective function such as growth or energy balance. Based on publicly available and in-house large scale transcriptomic data, metabolic models for melanoma were reconstructed, enabling the prediction of 28 candidate drugs and estimating their respective efficacy.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
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EGAD00001009089 | NextSeq 500 | 31 |
Publications | Citations |
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Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma.
Cell Death Dis 14: 2023 468 |
2 |