Exome sequencing in CLL re-treated with venetoclax

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001008685	The dataset contains whole exome sequencing data (libraries prepared using the Agilent SureSelect Human All Exon V6 kit, and paired-end sequenced on Illumina HiSeq4000 (2 x 150bp)) of 6 samples taken from peripheral blood mononuclear cells (PBMCs) (Samples 1-5) and bone marrow (BM). Data are provided as fastq files. Sample 1 was taken prior to initial venetoclax treatment. Sample 2 was taken as disease progression on venetoclax. Sample 3 was taken during response to BTK and PI3K inhibitor therapy. Sample 4 and the BM sample were taken at disease progression/prior to venetoclax re-treatment. And Sample 5 was taken during venetoclax re-treatment response.	Illumina HiSeq 4000	6

Publications	Citations
Successful Retreatment With Venetoclax in a Patient With Chronic Lymphocytic Leukemia. Jackson RA, Smith VM, Jayne S, Drewes C, Bens S, Siebert R, Dyer MJS, Walter HS. Hemasphere 6: 2022 e752	2