Genotyping by OncoArray and Global Screening Array for colorectal cancer risk prediction

The study was conducted to build a Polygenic risk scores (PRS) based on a reported set of 140 single nucleotide polymorphisms that were identified to be associated with a higher risk of colorectal cancer (CRC). Genotyping by OncoArray and Global Screening Array was performed using DNA extracted from blood samples collected at baseline of 187 participants who develop CRC and 176 randomly selected controls without diagnosis of CRC identified within 14 years of follow-up.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00010002165	Genotyping using Global Screening Array	Global Screening Array	50
EGAD00010002166	Genotyping using Illumina OncoArray BeadChip	Illumina OncoArray BeadChip	332

Publications	Citations
A microRNA panel compared to environmental and polygenic scores for colorectal cancer risk prediction. Raut JR, Schöttker B, Holleczek B, Guo F, Bhardwaj M, Miah K, Schrotz-King P, Brenner H. Nat Commun 12: 2021 4811	21