Integration of metabolomics, genomics and immune phenotypes reveals the causal roles of metabolites in disease

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00010002146	metabolite levels provided by UM platform (Creative Dynamics Inc, NY, USA) (the data is raw abundance. Mapping was applied on log10 transformed data)		482
EGAD00010002147	covarites phenotypes, including gender (1=Female/0=Male), age and contraceptive		482
EGAD00010002148	metabolite levels measured by general metabolomics (Boston, USA) (the data is raw abundance. Mapping was applied on log10 transformed data)	flow-injection TOF-M spectrometry.	482
EGAD00010002149	Genotype data from healthy Dutch individuals measured by Illumina humanOmniExpress Exome-8v1.0 SNP chip Calling by Opticall 7.0	Illumina humanOmniExpress Exome-8v1.0 SNP chip	482
EGAD00010002150	metabolite levels measured by Brainshake Metabolomics/Nightingale Health metabolic platform (log2)	Nightingale's technology	482

Publications	Citations
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease. Chu X, Jaeger M, Beumer J, Bakker OB, Aguirre-Gamboa R, Oosting M, Smeekens SP, Moorlag S, Mourits VP, Koeken VACM, de Bree C, Jansen T, Mathews IT, Dao K, Najhawan M, Watrous JD, Joosten I, Sharma S, Koenen HJPM, Withoff S, Jonkers IH, Netea-Maier RT, Xavier RJ, Franke L, Xu CJ, Joosten LAB, Sanna S, Jain M, Kumar V, Clevers H, Wijmenga C, Netea MG, Li Y. Genome Biol 22: 2021 198	29
The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses. Kuijpers Y, Chu X, Jaeger M, Moorlag SJCFM, Koeken VACM, Zhang B, de Nooijer A, Grondman I, Gupta MK, Janssen N, Mourits VP, de Bree LCJ, de Mast Q, van de Veerdonk FL, Joosten LAB, Li Y, Netea MG, Xu CJ. Front Immunol 13: 2022 859387	2

Publications

Citations

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.
Chu X, Jaeger M, Beumer J, Bakker OB, Aguirre-Gamboa R, Oosting M, Smeekens SP, Moorlag S, Mourits VP, Koeken VACM, de Bree C, Jansen T, Mathews IT, Dao K, Najhawan M, Watrous JD, Joosten I, Sharma S, Koenen HJPM, Withoff S, Jonkers IH, Netea-Maier RT, Xavier RJ, Franke L, Xu CJ, Joosten LAB, Sanna S, Jain M, Kumar V, Clevers H, Wijmenga C, Netea MG, Li Y. Genome Biol 22: 2021 198

The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.
Kuijpers Y, Chu X, Jaeger M, Moorlag SJCFM, Koeken VACM, Zhang B, de Nooijer A, Grondman I, Gupta MK, Janssen N, Mourits VP, de Bree LCJ, de Mast Q, van de Veerdonk FL, Joosten LAB, Li Y, Netea MG, Xu CJ. Front Immunol 13: 2022 859387