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The evolutionary dynamics of human colorectal cancer using single-gland spatial multi-omic profiling of DNA, RNA and chromatin.

Deciphering the mechanisms of colorectal cancer growth, progression and dissemination in each individual patient.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001007828 NextSeq 500 661
EGAD00001008140 NextSeq 500 1207
EGAD00001008642 Illumina NovaSeq 6000 527
Publications Citations
The co-evolution of the genome and epigenome in colorectal cancer.
Nature 611: 2022 733-743
40
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Nature 611: 2022 744-753
52
Contribution of pks<sup>+</sup> E. coli mutations to colorectal carcinogenesis.
Nat Commun 14: 2023 7827
12