G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL

We describe a patient with Ph-like ALL, in which leukemic cells harbored an in-frame fusion between the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2) and the KIT proto-oncogene.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

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Dataset ID	Description	Technology	Samples
EGAD00001007564	G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL: RNAseq for human sample	Illumina HiSeq 4000	1

Publications	Citations
G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL. Iacobucci I, Fukano R, D Friske J, Qu C, Janke LJ, Zhao Y, Baviskar P, A Backhaus E, Chockley P, Seth A, Laird AD, Advani AS, Mullighan CG. Blood Adv 6: 2022 3255-3259	0