Copied to clipboard!

Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls

Type: Epigenetics
Archiver: European Genome-phenome Archive (EGA)

1 Dataset 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006986	We created three technical replicates of cell-free DNA from AML patient plasma to assess batch effects and utility of spike-in controls for the cfMeDIP-seq method. Each set of samples were given to three different technicians with slightly different protocols. Details can be found in Wilson et al. "Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls".	Illumina NovaSeq 6000 NextSeq 550	15

Publications	Citations
Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls. Wilson SL, Shen SY, Harmon L, Burgener JM, Triche T, Bratman SV, De Carvalho DD, Hoffman MM. Cell Rep Methods 2: 2022 100294	7
A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection. Zeng Y, Abelman DD, Singhawansa A, Cheng N, Fang Y, Main SC, Bell E, Ye W, Luo P, Wilson SL, Stutheit-Zhao EY, Wong D, Znassi N, Chen K, Mohanraj S, Sanz-Garcia E, Notta F, Ghanekar A, Awadalla P, Lok BH, Hoffman MM, Kim RH, Zadeh G, De Carvalho DD, Bratman SV, Lupien M, Pugh TJ, He HH. Nat Cancer 7: 2026 384-398	0

Publications

Citations

Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls.
Wilson SL, Shen SY, Harmon L, Burgener JM, Triche T, Bratman SV, De Carvalho DD, Hoffman MM. Cell Rep Methods 2: 2022 100294

A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection.
Zeng Y, Abelman DD, Singhawansa A, Cheng N, Fang Y, Main SC, Bell E, Ye W, Luo P, Wilson SL, Stutheit-Zhao EY, Wong D, Znassi N, Chen K, Mohanraj S, Sanz-Garcia E, Notta F, Ghanekar A, Awadalla P, Lok BH, Hoffman MM, Kim RH, Zadeh G, De Carvalho DD, Bratman SV, Lupien M, Pugh TJ, He HH. Nat Cancer 7: 2026 384-398