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The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples

A surrogate marker based on the epigenome that captures these components in easily accessible epithelial tissue could potentially identify women at risk. The WID-BC-index identifies women with breast cancer based on a DNA methylation signature derived from cervical smear samples.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001008144 -
EGAD00001008145 -
EGAD00010002079 Illumina MethylationEPIC Array 1094
EGAD00010002080 Illumina MethylationEPIC Array 202
EGAD00010002081 Illumina MethylationEPIC Array 442
EGAD00010002082 Illumina MethylationEPIC Array 200
EGAD00010002470 Illumina MethylationEPIC Array 105
EGAD00010002471 Illumina MethylationEPIC Array 211
Publications Citations
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples.
Nat Commun 13: 2022 449
15
The DNA methylome of cervical cells can predict the presence of ovarian cancer.
Nat Commun 13: 2022 448
18
Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock.
Genome Biol 23: 2022 52
6
A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets.
J Clin Oncol 40: 2022 3828-3838
18
DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment.
NPJ Precis Oncol 7: 2023 99
0
Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis.
Cancer Res 84: 2024 1898-1914
6