RNA sequencing of subchondral bone from patients that underwent a joint replacement surgery due to osteoarthritis.

1 Dataset 4 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006197	This dataset contains RNA-seq (Illumina Hiseq 4000) from macroscopically preserved and lesioned OA subchondral bone of patients that underwent joint replacement surgery due to OA (N=48).	Illumina HiSeq 4000	48

Publications	Citations
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets. Tuerlings M, van Hoolwerff M, Houtman E, Suchiman EHED, Lakenberg N, Mei H, van der Linden EHMJ, Nelissen RRGHH, Ramos YYFM, Coutinho de Almeida R, Meulenbelt I. Arthritis Rheumatol 73: 2021 789-799	24
Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis. Tuerlings M, van Hoolwerff M, van Bokkum JM, Suchiman HED, Lakenberg N, Broekhuis D, Nelissen RGHH, Ramos YFM, Mei H, Cats D, Coutinho de Almeida R, Meulenbelt I. Rheumatology (Oxford) 61: 2022 3023-3032	8
Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis. Coutinho de Almeida R, Tuerlings M, Ramos Y, Den Hollander W, Suchiman E, Lakenberg N, Nelissen RGHH, Mei H, Meulenbelt I. Rheumatology (Oxford) 62: 2023 1669-1676	5
Comprehensive analysis on subchondral bone marrow lesions of human osteoarthritis by integrating bulk and single-cell transcriptomes. Zeng M, Wang X, Chen T, Ruan G, Li J, Xue S, Zhao Y, Hu Z, Xie Y, Fan T, Chen S, Li Y, Wang Q, Zhang Y, Zhang R, Lin L, Ding C, Zhu Z. BMC Musculoskelet Disord 24: 2023 677	3