Personalised Mapping of Tumour Development in Synchronous Colorectal Cancer Patients

We performed an in-depth characterisation of 12 tumours from 3 syCRC patients by analysing histopathological, whole genome sequencing and RNA-sequencing data. We assessed the extent of genetic overlap between synchronous tumours and examined associations between clinicopathological information and the molecular, microbial and immune features of each tumour genome.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

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Dataset ID	Description	Technology	Samples
EGAD00001006131	Here, we performed a characterisation of 12 tumours and matched normal samples from 3 syCRC patients by whole genome sequencing: Patient A (tumours A1 and A2), Patient B (tumours B1-B5), and Patient C (tumours C1-C5). Somatic SNVs, indels and stuructural variants were called.		3

Publications	Citations
Personalised mapping of tumour development in synchronous colorectal cancer patients. Thomas V, Cotter MB, Tosetto M, Khaw YL, Geraghty R, Winter DC, Ryan EJ, Sheahan K, Furney SJ. NPJ Genom Med 5: 2020 27	3