Prostate Cancer mitochondrial DNA heteroplasmies and mitochondrial gene expression

2 Datasets 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001005931	RNASeq data from paired malignant/benign prostate tissues	Illumina HiSeq 2500	32
EGAD00001005945	50 paired benign/cancer samples from prostate tissue generated in 2 different runs - on 3 plates on the IonTorrent Proton. Total of 200 fastq.gz single end runs. Read length ~300 bp. %GC 44 Sequences per file approx 1 Mio.	Ion Torrent Proton	100

Publications	Citations
OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. Schöpf B, Weissensteiner H, Schäfer G, Fazzini F, Charoentong P, Naschberger A, Rupp B, Fendt L, Bukur V, Giese I, Sorn P, Sant'Anna-Silva AC, Iglesias-Gonzalez J, Sahin U, Kronenberg F, Gnaiger E, Klocker H. Nat Commun 11: 2020 1487	65
Targeting valine catabolism to inhibit metabolic reprogramming in prostate cancer. Bidgood CL, Philp LK, Rockstroh A, Lehman M, Nelson CC, Sadowski MC, Gunter JH. Cell Death Dis 15: 2024 513	1