The role of the mammalian SWI/SNF chromatin remodeling complex in neuroendocrine prostate cancer
We sought to determine the effects of SMARCA4 and SMARCA2 depletion in prostate cancer cell lines. We performed siRNA-mediated knock-down of SMARCA4 and SMARCA2 in an androgen-sensitive (LNCaP) cell line and in a castration-resistant prostate cancer (CRPC)-adenocarcinoma cell line (22Rv1) and compared global transcriptional alterations using RNA-seq.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001005800 | Illumina HiSeq 2500 | 15 | |
EGAD00001006356 | Illumina HiSeq 2500 Illumina NovaSeq 6000 Ion Torrent S5 XL | 288 |
Publications | Citations |
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Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity.
Nat Commun 11: 2020 5549 |
65 |