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Single cell RNA seq of the developing human embryo brain

The study aims at identifying the cell types and lineages of the developing human brain.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006049	379 tissue samples from various parts of the developing human embryo brain were dissociated and single cells were collected and processed without bias for mRNA-seq using 10X chromium 3' protocol. Libraries were sequenced on Illumina NovaSeq and reads aligned against the human GRCh38 genome.	Illumina NovaSeq 6000	379

Publications	Citations
CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment. Zhang J, Hu G, Lu Y, Ren H, Huang Y, Wen Y, Ji B, Wang D, Wang H, Liu H, Ma N, Zhang L, Pan G, Qu Y, Wang H, Zhang W, Miao Z, Yao H. Nat Commun 15: 2024 5524	1
An integrative single-cell atlas for exploring the cellular and temporal specificity of genes related to neurological disorders during human brain development. Kim S, Lee J, Koh IG, Ji J, Kim HJ, Kim E, Park J, Park JE, An JY. Exp Mol Med 56: 2024 2271-2282	0