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Adenoma to Carcinoma transition in Colorectal Cancer

Although colorectal carcinoma development is well accepted as a step-wise and sequential process, it is commonly investigated using non-sequential adenoma and carcinoma samples. Here we compared molecular pathologies of the earliest carcinoma stages with those in their adenomatous precursors to unravel common and divergent genetic traits between matched neoplasms with a shared evolutionary history but different contemporary biology.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001004848 Ion Torrent PGM 100
EGAD00010001691 Beadarray 12
Publications Citations
Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression.
BMC Biol 18: 2020 116
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