TRACERx 100: RNAseq data from the first 100 TRACERx tumours
TRACERx (TRAcking Cancer Evolution through therapy (Rx)) is a prospective cohort study designed to investigate intratumor heterogeneity (ITH) in relation to clinical outcome, and to determine the clonal nature of driver events and evolutionary processes in early stage non-small cell lung cancer (NSCLC). This study looks at the multi-region RNAseq data from the TRACERx100 cohort with high enough quality RNA available. There is RNAseq data from 164 regions (64 patients).
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001004591 | Illumina HiSeq 4000 | 164 |
Publications | Citations |
---|---|
Neoantigen-directed immune escape in lung cancer evolution.
Nature 567: 2019 479-485 |
474 |
Understanding the impact of immune-mediated selection on lung cancer evolution.
Br J Cancer 124: 2021 1615-1617 |
3 |
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression.
Nat Biotechnol 40: 2022 1624-1633 |
29 |
The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer.
Nat Cancer 4: 2023 608-628 |
24 |
Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin.
J Clin Invest 133: 2023 e164397 |
6 |
Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion.
iScience 27: 2024 110529 |
0 |
Multiregional transcriptomic profiling provides improved prognostic insight in localized non-small cell lung cancer.
NPJ Precis Oncol 8: 2024 225 |
0 |