Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

Pancreatic neuroendocrine tumors (pNETs) are uncommon cancers arising from pancreatic islet cells. Here we report analysis of gene mutation, copy number and RNA expression of 57 sporadic well-differentiated pNETs.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

4 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001005489	Nimblegen SeqCap (sequence capture) deep targetted DNA sequencing pNET	Illumina HiSeq 2500	98
EGAD00001005494	Nimblegen SeqCap Custom Panel Sequencing for pNet	Illumina HiSeq 2500	96
EGAD00010001680	Illumina Infinium Human 450k methylation arrays	Illumina	17
EGAD00010001681	Affymetrix PrimeView Human Gene Expression	Affymetrix	56

Publications	Citations
Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer. Lawrence B, Blenkiron C, Parker K, Tsai P, Fitzgerald S, Shields P, Robb T, Yeong ML, Kramer N, James S, Black M, Fan V, Poonawala N, Yap P, Coats E, Woodhouse B, Ramsaroop R, Yozu M, Robinson B, Henare K, Koea J, Johnston P, Carroll R, Connor S, Morrin H, Elston M, Jackson C, Reid P, Windsor J, MacCormick A, Babor R, Bartlett A, Damianovich D, Knowlton N, Grimmond S, Findlay M, Print C. NPJ Genom Med 3: 2018 18	27

Publications

Citations

Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer.
Lawrence B, Blenkiron C, Parker K, Tsai P, Fitzgerald S, Shields P, Robb T, Yeong ML, Kramer N, James S, Black M, Fan V, Poonawala N, Yap P, Coats E, Woodhouse B, Ramsaroop R, Yozu M, Robinson B, Henare K, Koea J, Johnston P, Carroll R, Connor S, Morrin H, Elston M, Jackson C, Reid P, Windsor J, MacCormick A, Babor R, Bartlett A, Damianovich D, Knowlton N, Grimmond S, Findlay M, Print C. NPJ Genom Med 3: 2018 18