The genomic landscape of lung adenocarcinoma in East Asians

We performed exome sequencing of 210 and transcriptome sequencing of 181 LUADs of Chinese patients. For more details, please see publication "Genomic landscape of lung adenocarcinoma in East Asians" by Chen J. et. al. in Nature Genetics 2020. https://www.nature.com/articles/s41588-019-0569-6.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 3 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001004421	FASTQ files of the RNA-Seq data for both the normal and tumor samples for the study "Genomic landscape of lung adenocarcinoma in East Asians". For raw read count data as well as other metadata, please download from https://src.gisapps.org/OncoSG_public/study/summary?id=GIS031 by clicking the download icon next to the dataset title.	Illumina HiSeq 4000	260
EGAD00001004422	FASTQ files of the Exome-Seq data for both the normal and tumor samples for the study "Genomic landscape of lung adenocarcinoma in East Asians". For mutations and copy number variants called by this study, please download from https://src.gisapps.org/OncoSG_public/study/summary?id=GIS031 by clicking the download icon next to the dataset title.	Illumina HiSeq 4000	418

Publications	Citations
Identification of age- and immune-related gene signatures for clinical outcome prediction in lung adenocarcinoma. Zhou A, Zhang D, Kang X, Brooks JD. Cancer Med 12: 2023 17475-17490	2
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression. Lee YF, Phua CZJ, Yuan J, Zhang B, Lee MY, Kannan S, Chiu YHJ, Koh CWQ, Yap CK, Lim EKH, Chen J, Lim Y, Lee JJH, Skanderup AJ, Wang Z, Zhai W, Tan NS, Verma CS, Tay Y, Tan DSW, Tam WL. Genome Med 16: 2024 91	1
Analyzing sex imbalance in EGA and dbGaP biological databases: Recommendations for better practices. Ruiz-Serra V, Buslón N, Philippe OR, Saby D, Morales M, Pontes C, Andirkó AM, Holliday GL, Jené A, Moldes M, Rambla J, Valencia A, Rementeria MJ, Cortés A, Cirillo D. iScience 27: 2024 110831	0