Single-cell transcriptome sequencing of regulatory and conventional T cells in breast cancer patients and healthy individuals.

Identification of tumor-specific effects on gene expression profile of regulatory T cells and conventional T cells in humans, investigation of the clonal origin of regulatory T cells and impact analysis of tumor-specific conversion of conventional T cells into induced regulatory T cells on the peripheral regulatory T cell repertoire in humans.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 2 Publications

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Dataset ID	Description	Technology	Samples
EGAD00001004069	Identification of tumor-specific effects on gene expression profile of regulatory T cells and conventional T cells in humans, investigation of the clonal origin of regulatory T cells and impact analysis of tumor-specific conversion of conventional T cells into induced regulatory T cells on the peripheral regulatory T cell repertoire in humans.	Illumina HiSeq 2500	2304

Publications	Citations
Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients. Xydia M, Rahbari R, Ruggiero E, Macaulay I, Tarabichi M, Lohmayer R, Wilkening S, Michels T, Brown D, Vanuytven S, Mastitskaya S, Laidlaw S, Grabe N, Pritsch M, Fronza R, Hexel K, Schmitt S, Müller-Steinhardt M, Halama N, Domschke C, Schmidt M, von Kalle C, Schütz F, Voet T, Beckhove P. Nat Commun 12: 2021 1119	19
IL-2 and TCR stimulation induce expression and secretion of IL-32β by human T cells. Sanna FC, Benešová I, Pervan P, Krenz A, Wurzel A, Lohmayer R, Mühlbauer J, Wöllner A, Köhl N, Menevse AN, Stamova S, Volpin V, Beckhove P, Xydia M. Front Immunol 15: 2024 1437224	0

Publications

Citations

Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients.
Xydia M, Rahbari R, Ruggiero E, Macaulay I, Tarabichi M, Lohmayer R, Wilkening S, Michels T, Brown D, Vanuytven S, Mastitskaya S, Laidlaw S, Grabe N, Pritsch M, Fronza R, Hexel K, Schmitt S, Müller-Steinhardt M, Halama N, Domschke C, Schmidt M, von Kalle C, Schütz F, Voet T, Beckhove P. Nat Commun 12: 2021 1119

IL-2 and TCR stimulation induce expression and secretion of IL-32β by human T cells.
Sanna FC, Benešová I, Pervan P, Krenz A, Wurzel A, Lohmayer R, Mühlbauer J, Wöllner A, Köhl N, Menevse AN, Stamova S, Volpin V, Beckhove P, Xydia M. Front Immunol 15: 2024 1437224