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Copy-number signatures and mutational processes in ovarian carcinoma

This study contains the data underlying our approach for copy-number signature identification in high-grade serous ovarian cancer. The samples studied are part of the BriTROC-1 consortium, a national study into relapsed high-grade serous ovarian cancer. The dataset consists of shallow-whole genome sequencing of 300 samples from 143 patients with match tagged-amplicon sequencing of TP53. The study also contains deeper whole-genome sequencing of 48 cases.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001004172 Illumina HiSeq 2500 Illumina MiSeq 55
EGAD00001004173 Illumina HiSeq 2500 Illumina MiSeq 300
EGAD00001004174 Illumina HiSeq 2500 300
EGAD00001004189 HiSeq X Ten 111
Publications Citations
Copy number signatures and mutational processes in ovarian carcinoma.
Nat Genet 50: 2018 1262-1270
212
High-grade serous ovarian carcinoma organoids as models of chromosomal instability.
Elife 12: 2023 e83867
13