Comprehensive Molecular Analysis of Colon Cancer for the Identification and Validation of New Biomarkers

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001004826	This dataset consists of Illumina HiSeq 2000 Whole Exome Sequencing of 84 colorectal samples: 42 Tumor tissue samples and 42 Normal tissue samples (adjacent to tumor sites). 2x75bp paired-end sequencing reads: 2 fastq files per sample	Illumina HiSeq 2000	84
EGAD00001004827	This dataset consists of SOLiD small RNA-seq of 250 colorectal samples: 100 tumor tissue samples, 100 normal tissue samples (adjacent to tumor sites) and 50 matched control samples of healthy individuals. CSfasta and qual files converted to single fastq files prior to uploading.	AB SOLiD System	250
EGAD00010001253	Affymetrix SNP 6.0	Affymetrix SNP 6.0	245

Publications	Citations
Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component. Alonso MH, Aussó S, Lopez-Doriga A, Cordero D, Guinó E, Solé X, Barenys M, de Oca J, Capella G, Salazar R, Sanz-Pamplona R, Moreno V. Br J Cancer 117: 2017 421-431	90
Colon-specific eQTL analysis to inform on functional SNPs. Moreno V, Alonso MH, Closa A, Vallés X, Diez-Villanueva A, Valle L, Castellví-Bel S, Sanz-Pamplona R, Lopez-Doriga A, Cordero D, Solé X. Br J Cancer 119: 2018 971-977	15
Identifying causal models between genetically regulated methylation patterns and gene expression in healthy colon tissue. Díez-Villanueva A, Jordà M, Carreras-Torres R, Alonso H, Cordero D, Guinó E, Sanjuan X, Santos C, Salazar R, Sanz-Pamplona R, Moreno V. Clin Epigenetics 13: 2021 162	6
Copy-number intratumor heterogeneity increases the risk of relapse in chemotherapy-naive stage II colon cancer. Lahoz S, Archilla I, Asensio E, Hernández-Illán E, Ferrer Q, López-Prades S, Nadeu F, Del Rey J, Sanz-Pamplona R, Lozano JJ, Castells A, Cuatrecasas M, Camps J. J Pathol 257: 2022 68-81	6
COLONOMICS - integrative omics data of one hundred paired normal-tumoral samples from colon cancer patients. Díez-Villanueva A, Sanz-Pamplona R, Solé X, Cordero D, Crous-Bou M, Guinó E, Lopez-Doriga A, Berenguer A, Aussó S, Paré-Brunet L, Obón-Santacana M, Moratalla-Navarro F, Salazar R, Sanjuan X, Santos C, Biondo S, Diez-Obrero V, Garcia-Serrano A, Alonso MH, Carreras-Torres R, Closa A, Moreno V. Sci Data 9: 2022 595	7
Identification of a Twelve-microRNA Signature with Prognostic Value in Stage II Microsatellite Stable Colon Cancer. Moratalla-Navarro F, Díez-Villanueva A, Garcia-Serrano A, Closa A, Cordero D, Solé X, Guinó E, Sanz-Pamplona R, Sanjuan X, Santos C, Biondo S, Salazar R, Moreno V. Cancers (Basel) 15: 2023 3301	1