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Mutational_Analysis_of_Colorectal_PDX_models

Targeted exome sequencing of patient derived xenografts from primary colorectal tumours and liver metastases.

Type: Cancer Genomics
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 3 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001001872	Targeted exome sequencing of patient derived xenografts from primary colorectal tumours and liver metastases. This dataset contains all the data available for this study on 2016-01-06.	Illumina HiSeq 2000	333
EGAD00001003334	Targeted exome sequencing of patient derived xenografts from primary colorectal tumours and liver metastases. This dataset contains all the data available for this study on 2017-05-11.	Illumina HiSeq 2000	573

Publications	Citations
Patterns of genomic change in residual disease after neoadjuvant chemotherapy for estrogen receptor-positive and HER2-negative breast cancer. Chatzipli A, Bonnefoi H, MacGrogan G, Sentis J, Cameron D, Poncet C, EORTC 10994/BIG 1-00 Consortium, Iggo R. Br J Cancer 125: 2021 1356-1364	2
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Falcinelli M, Dell'Omo G, Grassi E, Mariella E, Leto SM, Scardellato S, Lorenzato A, Arena S, Bertotti A, Trusolino L, Bardelli A, d'Adda di Fagagna F. Cell Death Dis 14: 2023 96	1
Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts. Perron U, Grassi E, Chatzipli A, Viviani M, Karakoc E, Trastulla L, Brochier LM, Isella C, Zanella ER, Klett H, Molineris I, Schueler J, Esteller M, Medico E, Conte N, McDermott U, Trusolino L, Bertotti A, Iorio F. Nat Commun 15: 2024 9139	0