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ICGC PedBrain DNA methylation sequencing

DNA methylation profiling of 107 medulloblastoma and 8 control samples by high-coverage whole-genome bisulfite (WBGS) sequencing and Illumina Infinium HumanMethylation450k array.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000644 Illumina HiSeq 2000 42
EGAD00001001630 Illumina HiSeq 2000 108
EGAD00010000562 Illumina_HumanMethylation450 115
Publications Citations
NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.
Cancer Cell 33: 2018 435-449.e6
39
TelomereHunter - in silico estimation of telomere content and composition from cancer genomes.
BMC Bioinformatics 20: 2019 272
47
Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response.
Neuro Oncol 22: 2020 1327-1338
7
Base-resolution methylomes of gliomas bearing histone H3.3 mutations reveal a G34 mutant-specific signature shared with bone tumors.
Sci Rep 10: 2020 16162
8