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BLUEPRINT RNA-seq data for common cells in the haematopoietic lineages, from adult and cord blood samples.

RNA-seq data for common cells in the haematopoietic lineages, from adult and cord blood samples.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000675 Illumina HiSeq 2000 12
EGAD00001000903 Illumina HiSeq 2000 4
EGAD00001000904 Illumina HiSeq 2000 7
EGAD00001000908 Illumina HiSeq 2000 3
EGAD00001000911 Illumina HiSeq 2000 4
EGAD00001000912 Illumina HiSeq 2000 1
EGAD00001000928 Illumina HiSeq 2000 7
EGAD00001000933 Illumina HiSeq 2000 1
EGAD00001000937 Illumina HiSeq 2000 1
EGAD00001001129 Illumina HiSeq 2000 10
EGAD00001001132 Illumina HiSeq 2000 3
EGAD00001001137 Illumina HiSeq 2000 2
EGAD00001001142 Illumina HiSeq 2000 1
EGAD00001001145 Illumina HiSeq 2000 2
EGAD00001001148 Illumina HiSeq 2000 8
EGAD00001001153 Illumina HiSeq 2000 1
EGAD00001001159 Illumina HiSeq 2000 3
EGAD00001001163 Illumina HiSeq 2000 1
EGAD00001001164 Illumina HiSeq 2000 1
EGAD00001001165 Illumina HiSeq 2000 5
EGAD00001001166 Illumina HiSeq 2000 1
EGAD00001001170 Illumina HiSeq 2000 1
EGAD00001001171 Illumina HiSeq 2000 1
EGAD00001001172 Illumina HiSeq 2000 1
EGAD00001001173 Illumina HiSeq 2000 10
EGAD00001001174 Illumina HiSeq 2000 1
EGAD00001001175 Illumina HiSeq 2000 1
EGAD00001001177 Illumina HiSeq 2000 7
EGAD00001001178 Illumina HiSeq 2000 1
EGAD00001001181 Illumina HiSeq 2000 7
EGAD00001001199 Illumina HiSeq 2000 18
EGAD00001001202 Illumina HiSeq 2000 4
EGAD00001001469 Illumina HiSeq 2000 1
EGAD00001001474 Illumina HiSeq 2000 14
EGAD00001001477 Illumina HiSeq 2000 3
EGAD00001001478 Illumina HiSeq 2000 1
EGAD00001001480 Illumina HiSeq 2000 3
EGAD00001001483 Illumina HiSeq 2000 1
EGAD00001001488 Illumina HiSeq 2000 2
EGAD00001001489 Illumina HiSeq 2000 1
EGAD00001001496 Illumina HiSeq 2000 2
EGAD00001001500 Illumina HiSeq 2000 2
EGAD00001001504 Illumina HiSeq 2000 3
EGAD00001001506 Illumina HiSeq 2000 8
EGAD00001001512 Illumina HiSeq 2000 1
EGAD00001001520 Illumina HiSeq 2000 3
EGAD00001001521 Illumina HiSeq 2000 3
EGAD00001001525 Illumina HiSeq 2000 1
EGAD00001001526 Illumina HiSeq 2000 1
EGAD00001001531 Illumina HiSeq 2000 1
EGAD00001001534 Illumina HiSeq 2000 5
EGAD00001001535 Illumina HiSeq 2000 2
EGAD00001001540 Illumina HiSeq 2000 1
EGAD00001001542 Illumina HiSeq 2000 1
EGAD00001001543 Illumina HiSeq 2000 1
EGAD00001001544 Illumina HiSeq 2000 10
EGAD00001001546 Illumina HiSeq 2000 1
EGAD00001001547 Illumina HiSeq 2000 1
EGAD00001001550 Illumina HiSeq 2000 7
EGAD00001001551 Illumina HiSeq 2000 1
EGAD00001001555 Illumina HiSeq 2000 7
EGAD00001001566 Illumina HiSeq 2000 2
EGAD00001001579 Illumina HiSeq 2000 3
EGAD00001001582 Illumina HiSeq 2000 18
EGAD00001001586 Illumina HiSeq 2000 4
EGAD00001001593 Illumina HiSeq 2000 1
EGAD00001002287 Illumina HiSeq 2000 1
EGAD00001002288 Illumina HiSeq 2000 3
EGAD00001002289 Illumina HiSeq 2000 1
EGAD00001002295 Illumina HiSeq 2000 2
EGAD00001002299 Illumina HiSeq 2000 1
EGAD00001002308 Illumina HiSeq 2000 8
EGAD00001002315 Illumina HiSeq 2000 6
EGAD00001002320 Illumina HiSeq 2000 1
EGAD00001002321 Illumina HiSeq 2000 4
EGAD00001002323 Illumina HiSeq 2000 7
EGAD00001002326 Illumina HiSeq 2000 2
EGAD00001002332 Illumina HiSeq 2000 1
EGAD00001002334 Illumina HiSeq 2000 2
EGAD00001002336 Illumina HiSeq 2000 5
EGAD00001002339 Illumina HiSeq 2000 6
EGAD00001002341 Illumina HiSeq 2000 2
EGAD00001002343 Illumina HiSeq 2000 2
EGAD00001002345 Illumina HiSeq 2000 2
EGAD00001002347 Illumina HiSeq 2000 1
EGAD00001002348 Illumina HiSeq 2000 10
EGAD00001002349 Illumina HiSeq 2000 2
EGAD00001002351 Illumina HiSeq 2000 1
EGAD00001002352 Illumina HiSeq 2000 1
EGAD00001002353 Illumina HiSeq 2000 3
EGAD00001002356 Illumina HiSeq 2000 3
EGAD00001002358 Illumina HiSeq 2000 8
EGAD00001002359 Illumina HiSeq 2000 1
EGAD00001002365 Illumina HiSeq 2000 1
EGAD00001002366 Illumina HiSeq 2000 3
EGAD00001002375 Illumina HiSeq 2000 2
EGAD00001002380 Illumina HiSeq 2000 3
EGAD00001002387 Illumina HiSeq 2000 7
EGAD00001002401 Illumina HiSeq 2000 14
EGAD00001002402 Illumina HiSeq 2000 1
EGAD00001002409 Illumina HiSeq 2000 13
EGAD00001002414 Illumina HiSeq 2000 1
EGAD00001002417 Illumina HiSeq 2000 6
EGAD00001002422 Illumina HiSeq 2000 1
EGAD00001002426 Illumina HiSeq 2000 3
EGAD00001002436 Illumina HiSeq 2000 2
EGAD00001002438 Illumina HiSeq 2000 3
EGAD00001002443 Illumina HiSeq 2000 7
EGAD00001002446 Illumina HiSeq 2000 3
EGAD00001002452 Illumina HiSeq 2000 3
EGAD00001002456 Illumina HiSeq 2000 2
EGAD00001002461 Illumina HiSeq 2000 1
EGAD00001002465 Illumina HiSeq 2000 27
EGAD00001002467 Illumina HiSeq 2000 3
EGAD00001002469 Illumina HiSeq 2000 2
EGAD00001002471 Illumina HiSeq 2000 3
EGAD00001002473 Illumina HiSeq 2000 2
EGAD00001002476 Illumina HiSeq 2000 3
EGAD00001002479 Illumina HiSeq 2000 2
EGAD00001002482 Illumina HiSeq 2000 1
EGAD00001002500 Illumina HiSeq 2000 1
EGAD00001002507 Illumina HiSeq 2000 6
EGAD00001002509 Illumina HiSeq 2000 1
EGAD00001002513 Illumina HiSeq 2000 1
EGAD00001002518 Illumina HiSeq 2000 7
EGAD00001002525 Illumina HiSeq 2000 1
EGAD00001002526 Illumina HiSeq 2000 3
EGAD00001002671 Illumina HiSeq 2000 Illumina HiSeq 2500 212
EGAD00001002674 Illumina HiSeq 2000 Illumina HiSeq 2500 197
EGAD00001002675 Illumina HiSeq 2000 Illumina HiSeq 2500 205
EGAD00001002953 Illumina HiSeq 2000 8
EGAD00001002954 Illumina HiSeq 2000 1
EGAD00001002955 Illumina HiSeq 2000 1
EGAD00001002956 Illumina HiSeq 2000 2
EGAD00001002957 Illumina HiSeq 2000 1
EGAD00001002958 Illumina HiSeq 2000 1
EGAD00001002959 Illumina HiSeq 2000 1
EGAD00001002960 Illumina HiSeq 2000 1
EGAD00001002961 Illumina HiSeq 2000 1
EGAD00001002962 Illumina HiSeq 2000 1
EGAD00001002963 Illumina HiSeq 2000 6
EGAD00001002964 Illumina HiSeq 2000 1
EGAD00001002965 Illumina HiSeq 2000 1
EGAD00001002966 Illumina HiSeq 2000 1
EGAD00001002967 Illumina HiSeq 2000 1
EGAD00001002968 Illumina HiSeq 2000 2
EGAD00001004046 Illumina HiSeq 2000 NextSeq 500 303
Publications Citations
Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.
Cell 167: 2016 1369-1384.e19
573
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.
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364
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Genome Biol 18: 2017 18
62
Platelet function is modified by common sequence variation in megakaryocyte super enhancers.
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36
Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma.
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17
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21
Topological structure analysis of chromatin interaction networks.
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1
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7
Paired rRNA-depleted and polyA-selected RNA sequencing data and supporting multi-omics data from human T cells.
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13
DSAVE: Detection of misclassified cells in single-cell RNA-Seq data.
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1
Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation.
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Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation.
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A map of transcriptional heterogeneity and regulatory variation in human microglia.
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87
Logical modelling of <i>in vitro</i> differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions.
Interface Focus 11: 2021 20200061
5
Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions.
J Leukoc Biol 111: 2022 817-836
22
A compendium of uniformly processed human gene expression and splicing quantitative trait loci.
Nat Genet 53: 2021 1290-1299
171
HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors.
Nat Genet 54: 2022 393-402
31
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses.
Nat Commun 13: 2022 1779
18
Immune disease variants modulate gene expression in regulatory CD4<sup>+</sup> T cells.
Cell Genom 2: 2022 None
23
Differences in H3K4me3 and chromatin accessibility contribute to altered T-cell receptor signaling in neonatal naïve CD4 T cells.
Immunol Cell Biol 100: 2022 562-579
1
Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity.
Commun Biol 6: 2023 335
5
A computational method for cell type-specific expression quantitative trait loci mapping using bulk RNA-seq data.
Nat Commun 14: 2023 3030
2
Immune-response 3'UTR alternative polyadenylation quantitative trait loci contribute to variation in human complex traits and diseases.
Nat Commun 14: 2023 8347
1
Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma.
Nat Commun 15: 2024 6810
0
Trametinib Sensitivity is Defined by a Myeloid Differentiation Profile in Acute Myeloid Leukemia.
Drugs R D 24: 2024 489-499
0
LINE1 modulate human T cell function by regulating protein synthesis during the life span.
Sci Adv 10: 2024 eado2134
0