Osteosarcoma_Whole_Genome
We propose to definitively characterise the somatic genetics of Osteosarcoma cancer through generation of comprehensive catalogues of somatic mutations by high coverage genome sequencing.
- Type: Cancer Genomics
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001000147 | Illumina HiSeq 2000 | 108 | |
EGAD00001000646 | Illumina HiSeq 2000 | 14 | |
EGAD00001004163 | HiSeq X Ten Illumina HiSeq 2000 | 22 | |
EGAD00010000488 | Affymetrix_SNP6- | 7 |
Publications | Citations |
---|---|
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Nat Genet 45: 2013 1479-1482 |
424 |
Mutational signatures of ionizing radiation in second malignancies.
Nat Commun 7: 2016 12605 |
125 |
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.
Nat Commun 8: 2017 15936 |
115 |
Recurrent rearrangements of FOS and FOSB define osteoblastoma.
Nat Commun 9: 2018 2150 |
51 |
Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements.
Nat Genet 51: 2019 705-715 |
108 |
MYC amplifications are common events in childhood osteosarcoma.
J Pathol Clin Res 7: 2021 425-431 |
11 |
Epigenetic dysregulation from chromosomal transit in micronuclei.
Nature 619: 2023 176-183 |
35 |
Quantitative and qualitative mutational impact of ionizing radiation on normal cells.
Cell Genom 4: 2024 100499 |
0 |