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Xenograft_Sequencing

Sequencing of mouse/human carcinoma xenograft samples.

Type: Cancer Genomics
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001000143	Xenograft Seqeuncing	Illumina HiSeq 2000	16
EGAD00001001336	We propose to definitively characterise the somatic genetics of breast cancer through generation of comprehensive catalogues of somatic mutations in breast cancer cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.	Illumina HiSeq 2000	6

Publications	Citations
ERα-associated translocations underlie oncogene amplifications in breast cancer. Lee JJ, Jung YL, Cheong TC, Espejo Valle-Inclan J, Chu C, Gulhan DC, Ljungström V, Jin H, Viswanadham VV, Watson EV, Cortés-Ciriano I, Elledge SJ, Chiarle R, Pellman D, Park PJ. Nature 618: 2023 1024-1032	38
Complex rearrangements fuel ER<sup>+</sup> and HER2<sup>+</sup> breast tumours. Houlahan KE, Mangiante L, Sotomayor-Vivas C, Adimoelja A, Park S, Khan A, Pribus SJ, Ma Z, Caswell-Jin JL, Curtis C. Nature 638: 2025 510-518	0