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Integrative_Oncogenomics_of_Multiple_Myeloma

Agilent whole exome hybridisation capture will be performed on genomic DNA derived from Multiple Myeloma patient DNA and matched normal DNA from the same patients. Two lanes of Illumina GA sequencing will be performed on the resulting exome libraries and mapped to build 37 of the human reference genome to facilitate the identification of novel cancer genes.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000074 Illumina Genome Analyzer II Illumina HiSeq 2000 174
EGAD00001000339 Illumina Genome Analyzer II Illumina HiSeq 2000 154
EGAD00010000395 Affymetrix_SNP6 19
Publications Citations
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.
Nat Commun 5: 2014 2997
561
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Blood 132: 2018 587-597
256
Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.
Blood Cancer J 10: 2020 70
16
Genomic Classification and Individualized Prognosis in Multiple Myeloma.
J Clin Oncol 42: 2024 1229-1240
15