Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP
We conducted GWAS of sporadic CJD, variant CJD, iatrogenic CJD, inherited prion disease, kuru and resistance to kuru despite attendance at mortuary feasts. After quality control we analysed 2000 samples and 6015 control individuals (provided by the Wellcome Trust Case Control Consortium and KORA-gen), for 491032-511862 SNPs in the European study. Association studies were done in each geographical and aetiological group followed by several combined analyses.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00010000202 | Illumina_660K/Illumina_670K | 1478 |
| Publications | Citations |
|---|---|
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Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Hum Mol Genet 21: 2012 1897-1906 |
47 |