Evaluating gene expression in aggressive B-cell lymphoma using a quantitative nuclease protection assay
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL), comprising 25-30% of all NHL in developed countries with an annual incidence in the USA of 7 cases/100000 persons/year. Collectively, DLBCL is classified based on a common morphological appearance of diffuse growth of large transformed B-cells, immunophenotype, high proliferation rate and aggressive behaviour. Despite these similarities, DLBCLs are a heterogeneous collection of malignancies with distinct clinical and molecular characteristics that do not always correlate with immunohistological features. This gene expression dataset includes transcriptomes of ABC-DLBCLs and of GCB-DLBCLs where cell of origin is determined by the HTG-EdgeSeq quantitative nuclease protection assay. Also included are clonality results from BCR profiling from high-grade B-cell lymphomas sequenced using a NOVA sequencer
- 8 samples
- DAC: EGAC00001003392
- Technology: unspecified
Data Access Agreement for the Berardi Group
Data will be available to qualified investigators upon request
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001007479 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00008204536 | fastq.gz | 3.9 GB | ||
| EGAF00008204537 | fastq.gz | 4.0 GB | ||
| EGAF00008204538 | fastq.gz | 2.4 GB | ||
| EGAF00008204539 | fastq.gz | 2.4 GB | ||
| EGAF00008204540 | fastq.gz | 4.7 GB | ||
| EGAF00008204541 | fastq.gz | 4.9 GB | ||
| EGAF00008204542 | fastq.gz | 5.0 GB | ||
| EGAF00008204543 | fastq.gz | 5.3 GB | ||
| EGAF00008204544 | fastq.gz | 3.7 GB | ||
| EGAF00008204545 | fastq.gz | 3.9 GB | ||
| EGAF00008204546 | fastq.gz | 2.5 GB | ||
| EGAF00008204547 | fastq.gz | 2.5 GB | ||
| EGAF00008204548 | fastq.gz | 4.4 GB | ||
| EGAF00008204549 | fastq.gz | 4.6 GB | ||
| EGAF00008204550 | fastq.gz | 5.1 GB | ||
| EGAF00008204551 | fastq.gz | 5.2 GB | ||
| EGAF00008204552 | fastq.gz | 4.8 GB | ||
| EGAF00008204553 | fastq.gz | 5.0 GB | ||
| EGAF00008204554 | fastq.gz | 4.8 GB | ||
| EGAF00008204555 | fastq.gz | 5.0 GB | ||
| 20 Files (84.0 GB) | ||||