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Single-cell GoT sequencing from CH, MDS and AML patients with CH mutations

Single-cell targeted amplicon RNA sequencing from CH (n = 3), MDS (n = 6, MDS02 in 2 replicates) and AML (n =1, in 2 replicates) samples with mutations in splicing factors (SF3B1 - n = 8 [2 -CH, 6 MDS], U2AF1 n = 1) or transcription regulators (DNMT3A - CH04). The transcripts are targeted to detect a particular CH mutation in the listed genes. U2AF1 GoT are full-length cDNA, while the rest follow the 10x 3' V3 protocol.

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Details for GoT-Splice data access

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorized Personnel: The individuals at the User Institution to whom the Single-Cell Multiomics Data Team Access Committee grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorized Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Single-Cell Multiomics Data Team Access Committee and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. Single-Cell Multiomics Data Team Access Committee: 413 East 69th Street, Room 1428 New York, NY 10021

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007402 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008204227 fastq.gz 56.8 MB
EGAF00008204228 fastq.gz 58.3 MB
EGAF00008204229 fastq.gz 56.3 MB
EGAF00008204230 fastq.gz 57.8 MB
EGAF00008204231 fastq.gz 95.5 MB
EGAF00008204232 fastq.gz 87.7 MB
EGAF00008204233 fastq.gz 94.0 MB
EGAF00008204234 fastq.gz 87.4 MB
EGAF00008204235 fastq.gz 78.0 MB
EGAF00008204236 fastq.gz 231.4 MB
EGAF00008204237 fastq.gz 69.9 MB
EGAF00008204238 fastq.gz 206.5 MB
EGAF00008204239 fastq.gz 543.0 MB
EGAF00008204240 fastq.gz 751.1 MB
EGAF00008204241 fastq.gz 565.5 MB
EGAF00008204242 fastq.gz 439.4 MB
EGAF00008204243 fastq.gz 561.1 MB
EGAF00008204244 fastq.gz 433.7 MB
EGAF00008204245 fastq.gz 604.3 MB
EGAF00008204246 fastq.gz 448.2 MB
EGAF00008204247 fastq.gz 599.2 MB
EGAF00008204248 fastq.gz 442.5 MB
EGAF00008204249 fastq.gz 693.8 MB
EGAF00008204250 fastq.gz 534.5 MB
EGAF00008204251 fastq.gz 688.2 MB
EGAF00008204252 fastq.gz 527.9 MB
EGAF00008204253 fastq.gz 4.1 MB
EGAF00008204254 fastq.gz 6.6 MB
EGAF00008204255 fastq.gz 4.1 MB
EGAF00008204256 fastq.gz 6.7 MB
EGAF00008204257 fastq.gz 5.6 MB
EGAF00008204258 fastq.gz 7.1 MB
EGAF00008204259 fastq.gz 5.6 MB
EGAF00008204260 fastq.gz 7.2 MB
EGAF00008204261 fastq.gz 279.1 MB
EGAF00008204262 fastq.gz 298.8 MB
EGAF00008204263 fastq.gz 277.6 MB
EGAF00008204264 fastq.gz 291.3 MB
EGAF00008204265 fastq.gz 10.1 GB
EGAF00008204266 fastq.gz 11.5 GB
40 Files (31.9 GB)