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Evaluation of somatic mutations in cervicovaginal samples as a non-invasive method for the detection and molecular classification of endometrial cancer

Evaluation of somatic mutations in cervicovaginal samples as a non-invasive method for the detection and molecular classification of endometrial cancer

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Data Access Committee ICO/IDIBELL Endometrial Cancer

ICO-IDIBELL: Catalan Institute of Oncology and Bellvitge Biomedical research Institute, Av. Gran Via de l’Hospitalet, 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain Authorised Personnel: The individuals at the User Institution to whom ICO-IDIBELL grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: ICO-IDIBELL and the collaborators listed in Appendix I, responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. The Data Producers and the User Institutions are individually referred to hereinafter as the “Party” and collectively as the “Parties”. 1.The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data for the duration of this Agreement including any extension thereof and thereafter for a period of five (5) years following termination or expiry of this Agreement. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. Excluded from this obligation of confidentiality shall be any Confidential Information of which the User Institution can reasonably demonstrate that it (a) was previously known to the User Institution, or (b) is, and/or becomes, publicly available during said five (5) year period through no fault of the User Institution, or (c) is independently and lawfully developed by the User Institution. This obligation of confidentiality shall not apply to any disclosure required by law, provided that the User Institution shall notify the Data Producers of any disclosure required by law in sufficient time so that the Data Producers may contest such requirement, if the Data Producers so chooses. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. ICO-IDIBELL represents that the proper informed consent has been obtained for the Data and the transfer of the Data to the User Institution for the use by the User Institution for the purpose of the Project. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (https://wellcome.ac.uk/sites/default/files/wtd003207.pdf) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify ICO-IDIBELL within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify ICO-IDIBELL prior to any significant changes to the protocol for the Project. 14. The User Institution will notify ICO-IDIBELL as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. Parties may terminate this agreement by written notice to the other Party. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than ICO-IDIBELL. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. The User Institution will provide a copy of its Ethics Committee with approval of the Project. 18. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 19. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 20. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Spain and shall be subject to the exclusive jurisdiction of the Spanish courts. 21. According to the General Data Protection Regulation, User Institution and ICO-IDIBELL report that the data that appears in this agreement, as well as those derived from the management thereof, will be processed only for the purpose set out on Appendix I. User Institution and ICO-IDIBELL are responsible for the veracity and accuracy of the personal data communicated and authorize their collection and processed for the described purpose. These personal data will be provided and will be kept as long as the relationship between User Institution and ICO-IDIBELL is maintained, and once it is finished, to comply with the respective legal responsibilities. Data will be transferred only when regulation requires it. User Institution and ICO-IDIBELL have the right to file a claim with the Control Authority if they consider that their rights have been violated. 22. This agreement shall enter into force on the date of the last signature hereinbelow and shall be valid for a term of one (1) year However, the obligations of confidentiality and non-use of Confidential Information by the Parties shall not be extinguished and will remain in force as indicated at clause 2. 23. The Parties may extend the term of the present Agreement, if the desired results have not been achieved by the end of the term and / or the Parties want the Agreement to be extended. In the event of an extension, the Parties shall sign an extension of the Term before its ending. The present Agreement cannot be assigned neither by virtue of any law nor by any other means, without the prior consent in writing of the ICO-IDIBELL. 24. In addition to the cases specifically regulated by the applicable legislation in force, the Agreement shall be terminated in the following cases: a. By the expiration of the contractual term agreed. b. At any time, by mutual agreement in writing. c. By the breach by a Party of any of the obligations under the Agreement, as long as such breach is not remedied within a maximum period of thirty (30) days after written request for the remedy, unless such breach is irreparable or makes impossible the fulfillment of this Agreement to the complaining Party, in which case the termination may be immediate, and in any case without prejudice to any claim for damages that may correspond to either Party.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007396 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008121870 bam 687.6 MB
EGAF00008121871 bam 1.0 GB
EGAF00008121872 bam 1.1 GB
EGAF00008121873 bam 407.8 MB
EGAF00008121874 bam 952.8 MB
EGAF00008121875 bam 415.5 MB
EGAF00008121876 bam 505.5 MB
EGAF00008121877 bam 1.5 GB
EGAF00008121878 bam 870.5 MB
EGAF00008121879 bam 308.1 MB
EGAF00008121880 bam 617.8 MB
EGAF00008121881 bam 564.5 MB
EGAF00008121882 bam 572.0 MB
EGAF00008121883 bam 1.4 GB
EGAF00008121884 bam 569.6 MB
EGAF00008121885 bam 879.1 MB
EGAF00008121886 bam 1.5 GB
EGAF00008121887 bam 294.2 MB
EGAF00008121888 bam 342.6 MB
EGAF00008121889 bam 239.0 MB
EGAF00008121890 bam 717.0 MB
EGAF00008121891 bam 628.0 MB
EGAF00008121892 bam 915.7 MB
EGAF00008121893 bam 1.1 GB
EGAF00008121894 bam 838.4 MB
EGAF00008121895 bam 781.4 MB
EGAF00008121896 bam 434.9 MB
EGAF00008121897 bam 300.5 MB
EGAF00008121898 bam 763.5 MB
EGAF00008121899 bam 627.9 MB
EGAF00008121900 bam 245.4 MB
EGAF00008121901 bam 521.8 MB
EGAF00008121902 bam 779.8 MB
EGAF00008121903 bam 1.3 GB
EGAF00008121904 bam 2.1 GB
EGAF00008121905 bam 432.6 MB
EGAF00008121906 bam 543.3 MB
EGAF00008121907 bam 1.2 GB
EGAF00008121908 bam 899.6 MB
EGAF00008121909 bam 564.7 MB
EGAF00008121910 bam 613.7 MB
EGAF00008121911 bam 422.7 MB
EGAF00008121912 bam 1.0 GB
EGAF00008121913 bam 464.8 MB
EGAF00008121914 bam 617.5 MB
EGAF00008121915 bam 1.1 GB
EGAF00008121916 bam 1.1 GB
EGAF00008121917 bam 456.4 MB
EGAF00008121918 bam 768.9 MB
EGAF00008121919 bam 645.4 MB
EGAF00008121920 bam 885.6 MB
EGAF00008121921 bam 1.4 GB
EGAF00008121922 bam 1.2 GB
EGAF00008121923 bam 541.7 MB
EGAF00008121924 bam 1.0 GB
EGAF00008121925 bam 726.5 MB
EGAF00008121926 bam 706.8 MB
EGAF00008121927 bam 999.6 MB
EGAF00008121928 bam 2.7 GB
EGAF00008121929 bam 1.5 GB
EGAF00008121930 bam 2.2 GB
EGAF00008121931 bam 1.1 GB
EGAF00008121932 bam 2.2 GB
EGAF00008121933 bam 1.0 GB
EGAF00008121934 bam 2.7 GB
EGAF00008121935 bam 1.2 GB
EGAF00008121936 bam 1.0 GB
EGAF00008121937 bam 1.0 GB
EGAF00008121938 bam 1.3 GB
EGAF00008121939 bam 1.4 GB
EGAF00008121940 bam 1.0 GB
EGAF00008121941 bam 1.2 GB
EGAF00008121942 bai 2.9 MB
EGAF00008121943 bai 2.8 MB
EGAF00008121944 bai 2.0 MB
EGAF00008121945 bai 3.4 MB
EGAF00008121946 bai 2.5 MB
EGAF00008121947 bai 6.3 MB
EGAF00008121948 bai 3.0 MB
EGAF00008121949 bai 6.1 MB
EGAF00008121950 bai 3.2 MB
EGAF00008121951 bai 6.4 MB
EGAF00008121952 bai 3.8 MB
EGAF00008121953 bai 3.0 MB
EGAF00008121954 bai 5.6 MB
EGAF00008121955 bai 2.4 MB
EGAF00008121956 bai 6.4 MB
EGAF00008121957 bai 3.8 MB
EGAF00008121958 bai 4.4 MB
EGAF00008121959 bai 4.4 MB
EGAF00008121960 bai 2.5 MB
EGAF00008121961 bai 4.4 MB
EGAF00008121962 bai 6.2 MB
EGAF00008121963 bai 6.1 MB
EGAF00008121964 bai 4.5 MB
EGAF00008121965 bai 6.3 MB
EGAF00008121966 bai 3.3 MB
EGAF00008121967 bai 3.7 MB
EGAF00008121968 bai 6.2 MB
EGAF00008121969 bai 4.5 MB
EGAF00008121970 bai 6.2 MB
EGAF00008121971 bai 4.4 MB
EGAF00008121972 bai 3.2 MB
EGAF00008121973 bai 6.2 MB
EGAF00008121974 bai 3.3 MB
EGAF00008121975 bai 3.0 MB
EGAF00008121976 bai 2.3 MB
EGAF00008121977 bai 3.6 MB
EGAF00008121978 bai 4.1 MB
EGAF00008121979 bai 6.2 MB
EGAF00008121980 bai 3.9 MB
EGAF00008121981 bai 2.8 MB
EGAF00008121982 bai 1.9 MB
EGAF00008121983 bai 4.2 MB
EGAF00008121984 bai 2.0 MB
EGAF00008121985 bai 6.1 MB
EGAF00008121986 bai 3.1 MB
EGAF00008121987 bai 2.0 MB
EGAF00008121988 bai 4.2 MB
EGAF00008121989 bai 3.5 MB
EGAF00008121990 bai 2.0 MB
EGAF00008121991 bai 2.3 MB
EGAF00008121992 bai 2.0 MB
EGAF00008121993 bai 3.1 MB
EGAF00008121994 bai 3.8 MB
EGAF00008121995 bai 2.7 MB
EGAF00008121996 bai 3.3 MB
EGAF00008121997 bai 3.1 MB
EGAF00008121998 bai 3.2 MB
EGAF00008121999 bai 3.6 MB
EGAF00008122000 bai 2.0 MB
EGAF00008122001 bai 4.6 MB
EGAF00008122002 bai 2.1 MB
EGAF00008122003 bai 2.0 MB
EGAF00008122004 bai 3.8 MB
EGAF00008122005 bai 4.3 MB
EGAF00008122006 bai 3.5 MB
EGAF00008122007 bai 2.3 MB
EGAF00008122008 bai 6.6 MB
EGAF00008122009 bai 4.9 MB
EGAF00008122010 bai 3.0 MB
EGAF00008122011 bai 3.8 MB
EGAF00008122012 bai 4.2 MB
EGAF00008122013 bai 6.2 MB
144 Files (66.7 GB)