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Identification of Long Non-coding RNA Biomarker of Human Lupus Nephritis Disease Activity - Dataset

Total RNA paired-end sequencing was performed on whole blood samples from 74 Lupus nephritis (LN) patients and 20 healthy controls using Illumina NovaSeq 6000.

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Identification of Long Non-coding RNA Biomarker of Human Lupus Nephritis Disease Activity - Policy

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom BRFAA grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: BRFAA and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. BRFAA (Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou Street, Athina 115 27): Your Institution details here 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify BRFAA within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify BRFAA prior to any significant changes to the protocol for the Project. 14. The User Institution will notify BRFAA as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. BRFAA may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than BRFAA. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for BRFAA Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS (to be completed by the data producer before passing to applicant) Dataset reference (EGA Study ID and Dataset Details) Study ID: EGAS00001007117 Dataset ID: EGAD00001010932 Name of project that created the dataset Identification of Long Non-coding RNA Biomarker of Human Lupus Nephritis Disease Activity Names of other data producers/collaborators Specific limitations on areas of research Minimum protection measures required File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted.   APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used including analysis plan (1000 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title   APPENDIX III – PUBLICATION POLICY BRFAA intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. BRFAA anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 12 months after these data were first made available on the relevant hosting database, unless BRFAA has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with BRFAA.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007117 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008089077 fastq.gz 1.3 GB
EGAF00008089078 fastq.gz 1.3 GB
EGAF00008089079 fastq.gz 984.6 MB
EGAF00008089080 fastq.gz 1.0 GB
EGAF00008089081 fastq.gz 2.1 GB
EGAF00008089082 fastq.gz 2.1 GB
EGAF00008089083 fastq.gz 1.4 GB
EGAF00008089084 fastq.gz 1.4 GB
EGAF00008089085 fastq.gz 1.8 GB
EGAF00008089086 fastq.gz 1.8 GB
EGAF00008089087 fastq.gz 1.0 GB
EGAF00008089088 fastq.gz 1.0 GB
EGAF00008089089 fastq.gz 3.0 GB
EGAF00008089090 fastq.gz 3.1 GB
EGAF00008089091 fastq.gz 986.2 MB
EGAF00008089092 fastq.gz 995.8 MB
EGAF00008089093 fastq.gz 1.8 GB
EGAF00008089094 fastq.gz 1.8 GB
EGAF00008089095 fastq.gz 950.6 MB
EGAF00008089096 fastq.gz 967.7 MB
EGAF00008089097 fastq.gz 1.3 GB
EGAF00008089098 fastq.gz 1.3 GB
EGAF00008089099 fastq.gz 4.1 GB
EGAF00008089100 fastq.gz 4.2 GB
EGAF00008089101 fastq.gz 477.8 MB
EGAF00008089102 fastq.gz 486.7 MB
EGAF00008089103 fastq.gz 906.3 MB
EGAF00008089104 fastq.gz 938.9 MB
EGAF00008089105 fastq.gz 700.0 MB
EGAF00008089106 fastq.gz 716.8 MB
EGAF00008089107 fastq.gz 923.6 MB
EGAF00008089108 fastq.gz 944.8 MB
EGAF00008089109 fastq.gz 1.2 GB
EGAF00008089110 fastq.gz 1.3 GB
EGAF00008089111 fastq.gz 2.4 GB
EGAF00008089112 fastq.gz 2.5 GB
EGAF00008089113 fastq.gz 1.0 GB
EGAF00008089114 fastq.gz 1.1 GB
EGAF00008089115 fastq.gz 1.2 GB
EGAF00008089116 fastq.gz 1.2 GB
EGAF00008089117 fastq.gz 1.7 GB
EGAF00008089118 fastq.gz 1.8 GB
EGAF00008089119 fastq.gz 4.6 GB
EGAF00008089120 fastq.gz 4.7 GB
EGAF00008089121 fastq.gz 984.1 MB
EGAF00008089122 fastq.gz 1.0 GB
EGAF00008089123 fastq.gz 2.2 GB
EGAF00008089124 fastq.gz 2.3 GB
EGAF00008089125 fastq.gz 3.1 GB
EGAF00008089126 fastq.gz 3.2 GB
EGAF00008089127 fastq.gz 1.5 GB
EGAF00008089128 fastq.gz 1.5 GB
EGAF00008089129 fastq.gz 1.8 GB
EGAF00008089130 fastq.gz 1.9 GB
EGAF00008089131 fastq.gz 2.6 GB
EGAF00008089132 fastq.gz 2.7 GB
EGAF00008089133 fastq.gz 986.6 MB
EGAF00008089134 fastq.gz 1.0 GB
EGAF00008089135 fastq.gz 3.4 GB
EGAF00008089136 fastq.gz 3.5 GB
EGAF00008089137 fastq.gz 2.9 GB
EGAF00008089138 fastq.gz 3.0 GB
EGAF00008089139 fastq.gz 1.3 GB
EGAF00008089140 fastq.gz 1.3 GB
EGAF00008089141 fastq.gz 900.6 MB
EGAF00008089142 fastq.gz 932.3 MB
EGAF00008089143 fastq.gz 4.5 GB
EGAF00008089144 fastq.gz 4.6 GB
EGAF00008089145 fastq.gz 1.3 GB
EGAF00008089146 fastq.gz 1.3 GB
EGAF00008089147 fastq.gz 1.8 GB
EGAF00008089148 fastq.gz 1.8 GB
EGAF00008089149 fastq.gz 1.8 GB
EGAF00008089150 fastq.gz 1.8 GB
EGAF00008089151 fastq.gz 1.5 GB
EGAF00008089152 fastq.gz 1.5 GB
EGAF00008089153 fastq.gz 1.7 GB
EGAF00008089154 fastq.gz 1.8 GB
EGAF00008089155 fastq.gz 1.5 GB
EGAF00008089156 fastq.gz 1.5 GB
EGAF00008089157 fastq.gz 1.9 GB
EGAF00008089158 fastq.gz 1.9 GB
EGAF00008089159 fastq.gz 1.0 GB
EGAF00008089160 fastq.gz 1.1 GB
EGAF00008089161 fastq.gz 801.5 MB
EGAF00008089162 fastq.gz 815.6 MB
EGAF00008089163 fastq.gz 1.7 GB
EGAF00008089164 fastq.gz 1.7 GB
EGAF00008089165 fastq.gz 2.1 GB
EGAF00008089166 fastq.gz 2.1 GB
EGAF00008089167 fastq.gz 2.1 GB
EGAF00008089168 fastq.gz 2.2 GB
EGAF00008089169 fastq.gz 2.7 GB
EGAF00008089170 fastq.gz 2.8 GB
EGAF00008089171 fastq.gz 1.7 GB
EGAF00008089172 fastq.gz 1.7 GB
EGAF00008089173 fastq.gz 1.5 GB
EGAF00008089174 fastq.gz 1.6 GB
EGAF00008089175 fastq.gz 2.4 GB
EGAF00008089176 fastq.gz 2.4 GB
EGAF00008089177 fastq.gz 2.0 GB
EGAF00008089178 fastq.gz 2.0 GB
EGAF00008089179 fastq.gz 1.9 GB
EGAF00008089180 fastq.gz 2.0 GB
EGAF00008089181 fastq.gz 645.5 MB
EGAF00008089182 fastq.gz 663.7 MB
EGAF00008089183 fastq.gz 1.6 GB
EGAF00008089184 fastq.gz 1.7 GB
EGAF00008089185 fastq.gz 1.2 GB
EGAF00008089186 fastq.gz 1.3 GB
EGAF00008089187 fastq.gz 1.1 GB
EGAF00008089188 fastq.gz 1.1 GB
EGAF00008089189 fastq.gz 1.7 GB
EGAF00008089190 fastq.gz 1.7 GB
EGAF00008089191 fastq.gz 2.5 GB
EGAF00008089192 fastq.gz 2.5 GB
EGAF00008089193 fastq.gz 1.9 GB
EGAF00008089194 fastq.gz 1.9 GB
EGAF00008089195 fastq.gz 2.9 GB
EGAF00008089196 fastq.gz 2.9 GB
EGAF00008089197 fastq.gz 2.1 GB
EGAF00008089198 fastq.gz 2.1 GB
EGAF00008089199 fastq.gz 2.1 GB
EGAF00008089200 fastq.gz 2.2 GB
EGAF00008089201 fastq.gz 1.6 GB
EGAF00008089202 fastq.gz 1.6 GB
EGAF00008089203 fastq.gz 1.5 GB
EGAF00008089204 fastq.gz 1.6 GB
EGAF00008089205 fastq.gz 2.2 GB
EGAF00008089206 fastq.gz 2.3 GB
EGAF00008089207 fastq.gz 5.7 GB
EGAF00008089208 fastq.gz 5.8 GB
EGAF00008089209 fastq.gz 2.1 GB
EGAF00008089210 fastq.gz 2.1 GB
EGAF00008089211 fastq.gz 1.9 GB
EGAF00008089212 fastq.gz 2.0 GB
EGAF00008089213 fastq.gz 3.0 GB
EGAF00008089214 fastq.gz 3.1 GB
EGAF00008089215 fastq.gz 2.3 GB
EGAF00008089216 fastq.gz 2.4 GB
EGAF00008089217 fastq.gz 1.7 GB
EGAF00008089218 fastq.gz 1.7 GB
EGAF00008089219 fastq.gz 6.6 GB
EGAF00008089220 fastq.gz 6.9 GB
EGAF00008089221 fastq.gz 1.7 GB
EGAF00008089222 fastq.gz 1.7 GB
EGAF00008089223 fastq.gz 1.5 GB
EGAF00008089224 fastq.gz 1.6 GB
EGAF00008089225 fastq.gz 1.1 GB
EGAF00008089226 fastq.gz 1.2 GB
EGAF00008089227 fastq.gz 1.6 GB
EGAF00008089228 fastq.gz 1.6 GB
EGAF00008089229 fastq.gz 1.3 GB
EGAF00008089230 fastq.gz 1.4 GB
EGAF00008089231 fastq.gz 3.2 GB
EGAF00008089232 fastq.gz 3.2 GB
EGAF00008089233 fastq.gz 1.7 GB
EGAF00008089234 fastq.gz 1.7 GB
EGAF00008089235 fastq.gz 1.6 GB
EGAF00008089236 fastq.gz 1.7 GB
EGAF00008089237 fastq.gz 2.3 GB
EGAF00008089238 fastq.gz 2.4 GB
EGAF00008089239 fastq.gz 1.7 GB
EGAF00008089240 fastq.gz 1.8 GB
EGAF00008089241 fastq.gz 1.3 GB
EGAF00008089242 fastq.gz 1.3 GB
EGAF00008089243 fastq.gz 1.8 GB
EGAF00008089244 fastq.gz 1.9 GB
EGAF00008089245 fastq.gz 1.2 GB
EGAF00008089246 fastq.gz 1.2 GB
EGAF00008089247 fastq.gz 775.6 MB
EGAF00008089248 fastq.gz 791.0 MB
EGAF00008089249 fastq.gz 1.1 GB
EGAF00008089250 fastq.gz 1.1 GB
EGAF00008089251 fastq.gz 734.1 MB
EGAF00008089252 fastq.gz 758.2 MB
EGAF00008089253 fastq.gz 1.4 GB
EGAF00008089254 fastq.gz 1.5 GB
EGAF00008089255 fastq.gz 1.1 GB
EGAF00008089256 fastq.gz 1.2 GB
EGAF00008089257 fastq.gz 1.4 GB
EGAF00008089258 fastq.gz 1.4 GB
EGAF00008089259 fastq.gz 1.4 GB
EGAF00008089260 fastq.gz 1.4 GB
EGAF00008089261 fastq.gz 1.0 GB
EGAF00008089262 fastq.gz 1.0 GB
EGAF00008089263 fastq.gz 5.2 GB
EGAF00008089264 fastq.gz 5.4 GB
188 Files (356.8 GB)