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Bulk RNA-Seq

Human data for transcriptome (bulk RNA-Seq) in eight B-cell precursors: HSC, CLP, pro-B, pre-B, Immature B, Transitional B, Naive B CD5-, Naive B CD5+ cells

Request Access

This agreement governs the terms on which access will be granted to the data generated by the Centro de Investigación Médica Aplicada (CIMA) – Navarrabiomed B-cell Project.

THE CENTRO DE INVESTIGACIÓN MÉDICA APLICADA - NAVARRABIOMED B-CELL PROJECT DATA ACCESS AGREEMENT This agreement governs the terms on which access will be granted to the data generated by the Centro de Investigación Médica Aplicada (CIMA) – Navarrabiomed B-cell Project. These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions: BCP means the Centro de Investigación Médica Aplicada (CIMA) – Navarrabiomed B-cell Project Authorised Personnel means the individuals at the User Institution to whom BCP grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data means all and any human data obtained from the BCP. Data Producers means core laboratories responsible for the development, organization, and oversight of the Data. Research Participant means an individual whose data form part of these Data, after consent to use biological material for research. Project means the project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Research Purposes shall mean research seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User means a researcher whose User Institution has previously completed this Data Access Agreement and has received acknowledgement of its acceptance. User Institution means the organization where the User is employed, affiliated or enrolled. External Collaborator means a collaborator of the User, working for an institution other than the User Institution. Publications mean, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Terms and Conditions: In signing this Agreement: 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied, as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from using these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify BCP within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify BCP prior to any significant changes to the protocol for the Project. 14. The User Institution will notify BCP as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. BCP may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purposes in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. For example, this may include specific provisions relating to the Data required by Data Producers other than BCP. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes, and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Spain and shall be subject to the exclusive jurisdiction of the Spanish courts. For and on behalf of User (Copy and paste as many times as users) * Name of Applicant(s): Signature of Applicant(s): Title of Applicant(s): Date: * Must include Laboratory Head, Principal Investigator or Departmental Chair For and on behalf of User Institution ** Signature of Institutional or Administrative Authority: Print name: User Institution: Date: ** The Institutional or Administrative Authority is equivalent to the individual with the organizational authority to sign for a grant application, otherwise known as the Authorized Organizational Representative (AOR) or the Signing Official. Agreed for BCP Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS (to be completed by the data producer before passing to the applicant) Dataset reference (EGA Study ID and Dataset Details) Name of project that created the dataset Names of other data producers/collaborators Specific limitations on areas of research Minimum protection measures required File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used (500 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS000000000XX), and acknowledge its use using the following wording "This study makes use of data generated by the Centro de Investigación Médica Aplicada – Navarrabiomed” and cite the relevant primary BCP publication if one has been published.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007296 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008086618 fastq.gz 503.5 MB
EGAF00008086619 fastq.gz 498.8 MB
EGAF00008086620 fastq.gz 579.2 MB
EGAF00008086621 fastq.gz 539.0 MB
EGAF00008086622 fastq.gz 583.9 MB
EGAF00008086623 fastq.gz 496.2 MB
EGAF00008086624 fastq.gz 946.8 MB
EGAF00008086625 fastq.gz 517.1 MB
EGAF00008086626 fastq.gz 1.1 GB
EGAF00008086627 fastq.gz 674.0 MB
EGAF00008086628 fastq.gz 514.6 MB
EGAF00008086629 fastq.gz 525.6 MB
EGAF00008086630 fastq.gz 494.4 MB
EGAF00008086631 fastq.gz 548.4 MB
EGAF00008086632 fastq.gz 533.1 MB
EGAF00008086633 fastq.gz 555.5 MB
EGAF00008086634 fastq.gz 498.5 MB
EGAF00008086635 fastq.gz 773.1 MB
EGAF00008086636 fastq.gz 498.3 MB
EGAF00008086637 fastq.gz 523.1 MB
EGAF00008086638 fastq.gz 510.1 MB
EGAF00008086639 fastq.gz 880.1 MB
EGAF00008086640 fastq.gz 814.0 MB
EGAF00008086641 fastq.gz 502.6 MB
EGAF00008086642 fastq.gz 829.5 MB
EGAF00008086643 fastq.gz 873.9 MB
EGAF00008086644 fastq.gz 774.0 MB
EGAF00008086645 fastq.gz 1.3 GB
EGAF00008086646 fastq.gz 867.8 MB
EGAF00008086647 fastq.gz 795.5 MB
EGAF00008086648 fastq.gz 826.0 MB
EGAF00008086649 fastq.gz 1.4 GB
EGAF00008086650 fastq.gz 743.7 MB
EGAF00008086651 fastq.gz 591.9 MB
EGAF00008086652 fastq.gz 554.1 MB
EGAF00008086653 fastq.gz 508.4 MB
EGAF00008086654 fastq.gz 492.8 MB
EGAF00008086655 fastq.gz 709.2 MB
EGAF00008086656 fastq.gz 758.9 MB
EGAF00008086657 fastq.gz 552.2 MB
EGAF00008086658 fastq.gz 1.5 GB
EGAF00008086659 fastq.gz 1.1 GB
EGAF00008086660 fastq.gz 1.0 GB
EGAF00008086661 fastq.gz 893.8 MB
EGAF00008086662 fastq.gz 581.2 MB
EGAF00008086663 fastq.gz 976.4 MB
EGAF00008086664 fastq.gz 1.1 GB
EGAF00008086665 fastq.gz 728.4 MB
EGAF00008086666 fastq.gz 324.0 MB
EGAF00008086667 fastq.gz 841.3 MB
EGAF00008086668 fastq.gz 1.4 GB
EGAF00008086669 fastq.gz 1.2 GB
EGAF00008086670 fastq.gz 1.5 GB
EGAF00008086671 fastq.gz 476.7 MB
EGAF00008086672 fastq.gz 933.9 MB
EGAF00008086673 fastq.gz 1.1 GB
EGAF00008086674 fastq.gz 730.2 MB
EGAF00008086675 fastq.gz 787.3 MB
EGAF00008086676 fastq.gz 509.6 MB
EGAF00008086677 fastq.gz 519.0 MB
EGAF00008086678 fastq.gz 484.1 MB
EGAF00008086679 fastq.gz 537.4 MB
EGAF00008086680 fastq.gz 610.4 MB
EGAF00008086681 fastq.gz 831.1 MB
EGAF00008086682 fastq.gz 591.7 MB
EGAF00008086683 fastq.gz 490.0 MB
EGAF00008086684 fastq.gz 1.7 GB
EGAF00008086685 fastq.gz 1.2 GB
EGAF00008086686 fastq.gz 871.2 MB
EGAF00008086687 fastq.gz 954.0 MB
EGAF00008086688 fastq.gz 998.7 MB
EGAF00008086689 fastq.gz 494.1 MB
EGAF00008086690 fastq.gz 534.0 MB
EGAF00008086691 fastq.gz 376.1 MB
EGAF00008086692 fastq.gz 555.3 MB
EGAF00008086693 fastq.gz 55.0 MB
EGAF00008086694 fastq.gz 523.6 MB
EGAF00008086695 fastq.gz 631.6 MB
EGAF00008086696 fastq.gz 815.2 MB
79 Files (58.7 GB)