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HGSOC organoid sequencing study

sWGS dataset of 18 matched PDO and ascites samples, and scDNA sequencing of three of these PDOs.

Request Access

DAC to determine access to and use of the sWGS and scDNA HGSOC datasets

Data Access Request Form – Brenton Lab, CRUK-CI, University of Cambridge, UK These terms and conditions govern access to and use of the managed access datasets to which the User Institution has requested access. The User Institution and User agree to be bound by these terms and conditions. Definitions: - Confidential Information: means any information provided by the Data Provider relating to the Data - Data: The managed access dataset(s) to which the User Institution has requested access, as detailed in Schedule B. - Data Provider: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE of The Old Schools, Trinity Lane, Cambridge CB2 1TN, United Kingdom and the Cambridge University Hospitals NHS Foundation Trust of Addenbrooke’s Hospital, Cambridge, CB2 0QQ; represented by staff of the Brenton Group at the Cancer Research UK Cambridge Institute, and contactable by email at james.brenton@cruk.cam.ac.uk or future email as updated; or future representatives as indicated in Data Access Committee(s) for the dataset(s) defined in Schedule B. - Data Subject: means an individual who participated in research studies from whom the Data was derived. - External Collaborator: A collaborator of the User, working for an institution other than the User Institution. - Personal Data: means information and/or data about one or more living person who is the subject of personal data and who can be identified from that information, as provided under the General Data Protection Regulation (EU) 2016/679 (as amended from time to time), including but not limited to surname, initials, date of birth, address and postcodes, national insurance number, hospital number or NHS number. - Project: The research project for which the User Institution has requested access to these Data, as defined in Schedule B. - Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. - User: The principal investigator for the Project. - User Institution(s): The Institution that has requested access to the Data. User Institution is referred to within this Agreement as “You” (and “Your” shall be construed accordingly). 
Data Provider will provide access to Data to the User Institution under the following Terms and Conditions: 1.     You agree to preserve, at all times, the confidentiality and privacy of information and Data pertaining to Data Subjects. In particular, you undertake not to use, or attempt to use the Data to compromise or otherwise breach or infringe the confidentiality and privacy of information on Data Subjects. You agree to protect the confidentiality of Data Subjects in any Publications that you prepare by taking all reasonable care to limit the possibility of identification. You agree not to attempt to link Data to any other data source on the same samples, link the Data to any person or otherwise identify any Data Subject from the Data. 2.     You agree not to transfer or disclose the Data, in whole or part, to others, except to persons within the User Institution for carrying out the Project or as reasonably necessary for Data/safety monitoring or programme management. If You wish to disclose the Data to a collaborator outside the User Institution, the third party must make a separate application for access to the Data. 3.     You agree to use the Data for the advancement of medical research, and solely for the approved purpose and Project described in Schedule B and for no other purpose. 4.     You agree that Data may be reissued from time to time, with suitable versioning. If the reissue is at the request of Data Subjects and/or other ethical scrutiny or concerns, you will destroy earlier versions of the Data, and upon request of Data Provider, provide written certification of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 5.     You agree to acknowledge in any Publication based in whole or part on the Data, the published paper(s) from which the Data derives, and the version of the Data. 6.     You agree and acknowledge that the researchers of this study, the original Data creators, depositors, or copyright holders, and the Data Provider: a) bear no legal responsibility or liability for the accuracy or comprehensiveness of the Data, or from any use of the Data including further analysis or interpretation of such Data; and b) shall have no liability for any direct or indirect, consequential, or incidental damages or losses whatsoever arising out of Your use of the Data, or from the unavailability of, or lack of access to, the Data for whatever reason; and c) disclaim any and all representations, conditions or warranties (either express, implied or statutory) regarding the Data, including accuracy of the Data or that the Data corresponds with a particular description or is fit for a particular purpose. 7.     You understand and acknowledge that the Data is owned by Data Provider and its collaborators and is protected by copyright, database rights and other intellectual property rights. You agree that you shall not reproduce or copy the Data, except as reasonably required to carry out the Project and for no other purpose, or sell all or any part of the Data in any circumstances. 8.     You recognise that by granting You access to Data, no rights or ownership or intellectual property rights in or relating to the Data are transferred to You. 9.     Upon any breach by You of the terms set out in this form, You will be required to destroy the Data in Your possession, and upon request, provide written certification to the Data Provider of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 10.  You accept that it may be necessary for the Data Provider to alter the terms of use of the Data from time to time. As an example, this may include specific provisions relating to the Data required by Data Provider or collaborator parties. In the event that changes are required, the Data Provider or their appointed agent will contact You to inform You of the changes and You may elect either to accept the changes or to destroy the Data in Your possession and cease its use. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 11.  You agree that the Data is protected by and subject to applicable international laws. You are responsible for ensuring compliance with any such laws. The Data Provider reserves the right to request and inspect Your data security and management documentation to ensure the adequacy and compliance of data protection measures pertaining to storage and use of Data. 12.  If the Data includes any identifiable Personal Data, You agree to: (a) take appropriate technical and organisational measures against the unauthorised or unlawful processing and/or use of the Data, any data derived from the Data and/or and all Confidential Information, against the accidental loss or destruction of, or damage to, such data and information. (b) ensure that the measures referred to in (a) shall include the measures set out in Schedule A. (c) restrict access to the Data, any data derived from the Data and all other Confidential Information to employees who strictly need access to such data and/or information to undertake the Project, and shall ensure that all such employees are reliable, and informed of the confidential nature of such data and/or information and the importance of processing it securely. (d) For the avoidance of doubt, You undertake not to disclose to a third party, whether in connection with the Project or otherwise, any data and/or information contained in or derived from the Data which constitutes Personal Data.       Schedule A 1.1       You acknowledge and agree that the Data is pseudonymised Data and that You will become the Data Controller on receipt of such Data. 1.2       You will only process the Data for the purpose of carrying out the Project. 1.3       You agree that safeguards required under Article 89(1) of GDPR, and relevant conditions under the Data Protection Act 2018, are satisfied, and in particular that: (i) the processing of Data under or in connection with this Agreement is in the public interest; and (ii) if applicable, the Project has been subject to ethical review by an appropriate institutional review board or independent ethics committee. 1.4       The Data Provider does not intend to provide any information that may lead to You being able to identify any individual from whom any Data has been obtained. 1.5       You agree that You shall not analyse or make any use of any Data where it is reasonably foreseeable that such analysis or use may lead to the identification of any Data Subject or compromise the anonymity of any Data Subject in any way. 1.6       You shall notify the Data Provider immediately of any actual or suspected breach of security which involves the Data.   Schedule B - ame of the applicant and co-applicant(s), including affiliations, titles and contact details. 
For dataset deposited at EGA, applicants must have registered accounts at EGA. 
Student applicants must include their supervisors as a co-applicant.   Name of Registered User Email Job Title Supervisor*   - Title of Project (in less than 30 words)   - Data Requested (please indicate relevant publication(s) describing the data, accession number(s) and/or relevant links to data, and [where relevant] details of and links to the respective Data Access Committee(s) (DAC)) - Research Project: Please provide a clear description of the project and its specific aims in no more than 750 words. This should include specific details of what you plan to do with the data and include key references. - Brief description of the infrastructure and experience for handling the requested data securely - Signature of authorized signatory of User Institution   Signature: Name: Title: Date:   Signature of Principal Investigator   I confirm that I have read and understood the TERMS AND CONDITIONS as set forth in this DATA ACCESS REQUEST FORM.   Signature: Name: Title: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007189 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008043148 fq.gz 906.0 MB
EGAF00008043149 fq.gz 409.6 MB
EGAF00008043150 fq.gz 464.3 MB
EGAF00008043151 fq.gz 277.8 MB
EGAF00008043152 fq.gz 799.4 MB
EGAF00008043153 fq.gz 555.2 MB
EGAF00008043154 fq.gz 418.9 MB
EGAF00008043155 fq.gz 760.5 MB
EGAF00008043156 fq.gz 603.9 MB
EGAF00008043157 fq.gz 791.4 MB
EGAF00008043158 fq.gz 660.4 MB
EGAF00008043159 fq.gz 611.5 MB
EGAF00008043160 fq.gz 551.3 MB
EGAF00008043161 fq.gz 540.4 MB
EGAF00008043162 fq.gz 614.5 MB
EGAF00008043163 fq.gz 1.6 GB
EGAF00008043164 fq.gz 653.3 MB
EGAF00008043165 fq.gz 1.2 GB
EGAF00008043166 fq.gz 581.1 MB
EGAF00008043167 fq.gz 366.6 MB
EGAF00008043168 cram 225.5 MB
EGAF00008043169 cram 128.1 MB
EGAF00008043170 cram 166.3 MB
EGAF00008043171 cram 180.9 MB
EGAF00008043172 cram 145.7 MB
EGAF00008043173 cram 81.0 MB
EGAF00008043174 cram 253.7 MB
EGAF00008043175 cram 190.2 MB
EGAF00008043176 cram 152.3 MB
EGAF00008043177 cram 88.9 MB
EGAF00008043178 cram 260.7 MB
EGAF00008043179 cram 106.0 MB
EGAF00008043180 cram 131.4 MB
EGAF00008043181 cram 99.3 MB
EGAF00008043182 cram 50.3 MB
EGAF00008043183 cram 134.2 MB
EGAF00008043184 cram 200.0 MB
EGAF00008043185 cram 224.0 MB
EGAF00008043186 cram 33.9 MB
EGAF00008043187 cram 167.7 MB
EGAF00008043188 cram 110.8 MB
EGAF00008043189 cram 109.6 MB
EGAF00008043190 cram 67.8 MB
EGAF00008043191 cram 204.9 MB
EGAF00008043192 cram 223.2 MB
EGAF00008043193 cram 210.7 MB
EGAF00008043194 cram 173.6 MB
EGAF00008043195 cram 210.0 MB
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EGAF00008043198 cram 160.0 MB
EGAF00008043199 cram 220.9 MB
EGAF00008043200 cram 218.5 MB
EGAF00008043201 cram 241.7 MB
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EGAF00008043203 cram 119.5 MB
EGAF00008043204 cram 98.0 MB
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EGAF00008043206 cram 95.4 MB
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EGAF00008043208 cram 155.1 MB
EGAF00008043209 cram 142.1 MB
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EGAF00008043213 cram 186.9 MB
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EGAF00008043216 cram 186.1 MB
EGAF00008043217 cram 262.3 MB
EGAF00008043218 cram 137.6 MB
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EGAF00008043223 cram 140.6 MB
EGAF00008043224 cram 219.5 MB
EGAF00008043225 cram 148.8 MB
EGAF00008043226 cram 103.9 MB
EGAF00008043227 cram 103.8 MB
EGAF00008043228 cram 135.9 MB
EGAF00008043229 cram 260.4 MB
EGAF00008043230 cram 148.5 MB
EGAF00008043231 cram 51.2 MB
EGAF00008043232 cram 169.3 MB
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EGAF00008043235 cram 115.8 MB
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EGAF00008043237 cram 228.8 MB
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EGAF00008043240 cram 199.9 MB
EGAF00008043241 cram 61.3 MB
EGAF00008043242 cram 195.5 MB
EGAF00008043243 cram 220.7 MB
EGAF00008043244 cram 183.2 MB
EGAF00008043245 cram 155.0 MB
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EGAF00008043250 cram 79.8 MB
EGAF00008043251 cram 159.1 MB
EGAF00008043252 cram 171.6 MB
EGAF00008043253 cram 129.2 MB
EGAF00008043254 cram 225.4 MB
EGAF00008043255 cram 140.1 MB
EGAF00008043256 cram 249.7 MB
EGAF00008043257 cram 78.4 MB
EGAF00008043258 cram 169.1 MB
EGAF00008043259 cram 104.3 MB
EGAF00008043260 cram 218.4 MB
EGAF00008043261 cram 228.0 MB
EGAF00008043262 cram 48.1 MB
EGAF00008043263 cram 158.7 MB
EGAF00008043264 cram 172.0 MB
EGAF00008043265 cram 67.7 MB
EGAF00008043266 cram 182.9 MB
EGAF00008043267 cram 213.1 MB
EGAF00008043268 cram 31.4 MB
EGAF00008043269 fq.gz 495.2 MB
EGAF00008043270 fq.gz 322.0 MB
EGAF00008043271 cram 41.1 MB
EGAF00008043272 cram 151.4 MB
EGAF00008043273 cram 98.6 MB
EGAF00008043274 cram 87.1 MB
EGAF00008043275 cram 102.4 MB
EGAF00008043276 cram 276.2 MB
EGAF00008043277 cram 47.8 MB
EGAF00008043278 cram 104.3 MB
EGAF00008043279 cram 217.3 MB
EGAF00008043280 cram 199.1 MB
EGAF00008043281 cram 90.6 MB
EGAF00008043282 cram 175.9 MB
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EGAF00008043287 cram 63.2 MB
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EGAF00008043307 cram 280.3 MB
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EGAF00008043312 cram 175.9 MB
EGAF00008043313 cram 264.1 MB
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EGAF00008043315 cram 92.2 MB
EGAF00008043316 cram 96.6 MB
EGAF00008043317 cram 270.0 MB
EGAF00008043318 cram 41.7 MB
EGAF00008043319 cram 78.1 MB
EGAF00008043320 cram 157.1 MB
EGAF00008043321 cram 135.1 MB
EGAF00008043322 cram 79.9 MB
EGAF00008043323 cram 119.4 MB
EGAF00008043324 cram 109.3 MB
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EGAF00008043326 cram 251.1 MB
EGAF00008043327 cram 200.3 MB
EGAF00008043328 cram 275.1 MB
EGAF00008043329 cram 77.9 MB
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EGAF00008043331 cram 171.2 MB
EGAF00008043332 cram 54.3 MB
EGAF00008043333 cram 123.1 MB
EGAF00008043334 cram 137.5 MB
EGAF00008043335 cram 84.1 MB
EGAF00008043336 cram 155.1 MB
EGAF00008043337 cram 181.5 MB
EGAF00008043338 cram 311.2 MB
EGAF00008043339 cram 127.1 MB
EGAF00008043340 cram 63.4 MB
EGAF00008043341 cram 93.5 MB
EGAF00008043342 cram 111.8 MB
EGAF00008043343 cram 90.2 MB
EGAF00008043344 cram 132.8 MB
EGAF00008043345 cram 41.8 MB
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EGAF00008043347 cram 136.9 MB
EGAF00008043348 cram 215.5 MB
EGAF00008043349 cram 66.6 MB
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EGAF00008043352 cram 126.2 MB
EGAF00008043353 cram 46.1 MB
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EGAF00008043355 cram 40.0 MB
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EGAF00008043365 cram 174.7 MB
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EGAF00008043370 cram 39.9 MB
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EGAF00008043376 cram 101.1 MB
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EGAF00008043385 cram 229.2 MB
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EGAF00008043387 cram 223.1 MB
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EGAF00008043391 cram 173.2 MB
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EGAF00008043403 cram 57.3 MB
EGAF00008043404 cram 274.9 MB
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EGAF00008043406 cram 243.3 MB
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EGAF00008043412 cram 173.1 MB
EGAF00008043413 cram 198.7 MB
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EGAF00008043416 cram 42.4 MB
EGAF00008043417 cram 291.4 MB
EGAF00008043418 cram 163.0 MB
EGAF00008043419 cram 79.9 MB
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EGAF00008043421 cram 93.3 MB
EGAF00008043422 cram 187.5 MB
EGAF00008043423 cram 591.0 MB
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EGAF00008043426 cram 59.5 MB
EGAF00008043427 cram 273.3 MB
EGAF00008043428 cram 83.3 MB
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EGAF00008043432 cram 244.3 MB
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EGAF00008043437 cram 238.3 MB
EGAF00008043438 cram 340.1 MB
EGAF00008043439 cram 128.8 MB
EGAF00008043440 cram 226.3 MB
EGAF00008043441 cram 200.4 MB
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EGAF00008043463 cram 46.7 MB
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EGAF00008043467 fq.gz 322.8 MB
EGAF00008043468 fq.gz 244.5 MB
EGAF00008043469 fq.gz 535.4 MB
EGAF00008043470 fq.gz 998.2 MB
EGAF00008043471 fq.gz 374.1 MB
EGAF00008043472 fq.gz 254.1 MB
EGAF00008043473 cram 130.4 MB
EGAF00008043474 cram 168.9 MB
EGAF00008043475 cram 155.1 MB
EGAF00008043476 cram 138.3 MB
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EGAF00008043478 cram 225.8 MB
EGAF00008043479 cram 169.7 MB
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EGAF00008043481 cram 128.5 MB
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EGAF00008043483 cram 132.8 MB
EGAF00008043484 cram 348.2 MB
EGAF00008043485 cram 213.8 MB
EGAF00008043486 cram 174.4 MB
EGAF00008043487 cram 44.9 MB
EGAF00008043488 cram 370.2 MB
EGAF00008043489 cram 79.5 MB
EGAF00008043490 cram 204.5 MB
EGAF00008043491 cram 179.0 MB
EGAF00008043492 cram 175.9 MB
EGAF00008043493 cram 124.5 MB
EGAF00008043494 cram 234.9 MB
EGAF00008043495 cram 242.8 MB
EGAF00008043496 cram 131.3 MB
EGAF00008043497 cram 187.1 MB
EGAF00008043498 cram 289.8 MB
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EGAF00008043501 cram 153.9 MB
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EGAF00008043503 cram 167.0 MB
EGAF00008043504 cram 169.4 MB
EGAF00008043505 cram 230.6 MB
EGAF00008043506 cram 81.5 MB
EGAF00008043507 cram 144.2 MB
EGAF00008043508 cram 263.2 MB
EGAF00008043509 cram 340.0 MB
EGAF00008043510 cram 277.8 MB
EGAF00008043511 cram 115.7 MB
EGAF00008043512 cram 101.4 MB
EGAF00008043513 cram 134.4 MB
EGAF00008043514 cram 211.5 MB
EGAF00008043515 cram 210.9 MB
EGAF00008043516 cram 180.0 MB
EGAF00008043517 cram 149.5 MB
EGAF00008043518 cram 129.1 MB
EGAF00008043519 cram 164.4 MB
EGAF00008043520 cram 55.2 MB
EGAF00008043521 cram 129.6 MB
EGAF00008043522 cram 91.1 MB
EGAF00008043523 cram 143.5 MB
EGAF00008043524 cram 172.8 MB
EGAF00008043525 cram 140.0 MB
EGAF00008043526 cram 77.4 MB
EGAF00008043527 cram 55.3 MB
EGAF00008043528 cram 266.0 MB
EGAF00008043529 cram 94.8 MB
EGAF00008043530 cram 196.2 MB
EGAF00008043531 cram 105.0 MB
EGAF00008043532 cram 211.7 MB
EGAF00008043533 cram 235.7 MB
EGAF00008043534 cram 121.9 MB
EGAF00008043535 cram 245.9 MB
EGAF00008043536 cram 98.2 MB
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EGAF00008043866 cram 224.2 MB
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EGAF00008043870 cram 245.2 MB
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EGAF00008043872 cram 241.2 MB
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EGAF00008043875 cram 67.7 MB
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EGAF00008043878 cram 77.4 MB
EGAF00008043879 cram 196.4 MB
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EGAF00008043881 cram 158.3 MB
EGAF00008043882 cram 117.2 MB
EGAF00008043883 cram 185.8 MB
EGAF00008043884 fq.gz 507.4 MB
EGAF00008043885 fq.gz 281.8 MB
EGAF00008043886 fq.gz 512.4 MB
EGAF00008043887 fq.gz 656.5 MB
EGAF00008043888 fq.gz 505.9 MB
EGAF00008043889 fq.gz 510.9 MB
EGAF00008043890 fq.gz 661.6 MB
EGAF00008043891 fq.gz 709.2 MB
744 Files (130.3 GB)