IntEnd study
Formalin-fixed, paraffin-embedded samples from 643 colorectal adenomas collected in different hospitals in Norway, from which DNA was extracted, were analysed for DNA copy number alterations. Some adenomas had more than one block (n=42), thus 643 individuals, 685 blocks. Low-coverage whole genome sequencing was run in all samples. For 529 individuals all the clinical information was available. A subset was matched for follow-up time, age and sex in a nested case-control approach (n=366; cases - individuals who developed later on CRC; controls - individuals who did not develop CRC within the same follow-up time).
- 685 samples
- DAC: EGAC00001003134
- Technology: Illumina HiSeq 2500
NKI Data Policy
To request access to the IntEnd dataset, please provide the following information in your Data Access Request: - Recipient and Recipient Institution - Details of dataset requested, i.e. EGA Study and Dataset Accession Number(s) - Brief abstract of the Project in which the Data will be used (500 words max.) - All Individuals who will be allowed access to the requested datasets by the Recipient Institution After receipt and review of your Data Access Request by the Data Access Committee, you will receive a Data Transfer Agreement to be completed, signed and returned to the Data Access Committee, prior to being granted access to the requested dataset(s). For the avoidance of doubt, the Data Access Committee reserves the right to withhold granting access.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
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